NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG TRÊN NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG TRÊN BỆNH NHÂN NHIỄM KHUẨN HUYẾT VÀ SỐC NHIỄM KHUẨN TẠI BỆNH VIỆN ĐA KHỆNH NHÂN NHIỄM KHUẨN HUYẾT VÀ SỐC NHIỄM KHUẨN TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ

Abstract

Background: Sepsis or septic shock is the systemic inflammatory response syndrome secondary to infection. Objectives: Describing the clinical and laboratory characteristics of septic and septic shock patients. Materials and methods: 92 patients with sepsis and septic shock were treated at Intensive Care Unit and Poisoning Control Department in Can Tho General Hospital and prospective descriptive cross-sectional study. Results: The clinical characteristics: Glasgow live group was 14.0±2.4, mortality group was 12.8±2.8; the living group had circuit 108.1±19.3 times/minute, the group died of pulse faster than 125±14.7 times/minute; the temperature of death group is 38.6°C, living group is 37.7 degrees C; SOFA in the living group was 6.9 points, the mortality group was 8.5 points (p<0.05). Circulatory failure 82.6%, respiratory failure 71.7%, ARDS 30.4%, renal failure 56.5%, liver failure 41.3%. The damage to 4 organs accounts for 23.9%, 3 organs for injury 22.8%, and 2 organs for 21.7%. The average number of impaired organs was 3.1±1.5. The laboratory characteristics: HCO₃ live group 12.7, death group 10.9; pH in the living group was 7.3 ± 0.2, the death group was only 7.1±0.5; The PaO₂ in the living group was 75.7, the mortality was lower than 60.8 (p<0.05); the living group had a high platelet of 175.4/mm³, the platelet mortality group 129.5/mm³, the GPT group died 151.4 mmol/l, the living group was 96.3 mmol/l (p<0.05). Blood lactate live group 6.4 mmol/l, death group 9.3mmol/l (p=0.035). The rate of positive blood cultures accounted for 36.5%, gram-negative bacteria accounted for 86.9%, Ecoli accounted for the majority of 39.1%; Gram-negative sputum culture 83.3% of Acinetobacter baumannii bacteria, majority of E.coli urine culture, total positive samples accounted for 45.6%. Conclusions: Altered perception, rapid pulse, high fever, high SOFA score, higher number of organs, decreased HCO₃, low blood pH, low PaO₂, thrombocytopenia, increased GPT, lactate elevated blood is a factor associated with death.