TÌNH HÌNH SỬ DỤNG KHÁNG SINH TRONG ĐIỀU TRỊ VIÊM PHỔI CỘNG ĐỒNG TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2020-2021

Abstract

Background: The appropriateness of initial antimicrobial regimen are very important in the treatment of community-acquired pneumonia. Objectives: To identify characteristics of antibiotic use, the rationality of antibiotic indication, and to identify bacterial pathogens of CAP. Materials and methods: A cross-sectional descriptive study on 207 medical records of inpatients diagnosed with CAP at the General Internal Medicine Department of Can Tho University of Medicine and Pharmacy Hospital from 01/01/2020 to 30/04/2021. Results: Antibiotics were used in the treatment for CAP: the β-lactam group accounted for the highest proportion, with penicillins 16.3%, cephalosporins 21.9%, and carbapenem 16.9%. Fluoroquinolones accounted  for 40.42%. Levofloxacin is the most prescribed antibiotic, accounting for 10.1%. Antibiotic regimens, antibiotic monotherapy accounted for 51.2%, the regimen of 2 antibiotics accounted for 46.8%, the regimen of 3 antibiotics accounted for 1.9%. There were 54.6% of the starting antibiotic regimen was consistent with the treatment guidelines of the Ministry of Health issued in 2015 and 57.9% of appropriate starting antibiotic regimens since results of bacterial culture and antibiogram. Bacterial pathogens were Acinetobacter baumanii, Pseudomonas aeruginosa, Klebsiella pneumoniae and Haemophilus influenzae. Conclusion: The use of antibiotics in the treatment of community-acquired pneumonia is mainly empiric because the cause is often unknown. Large-scale prospective studies are needed to confirm the need for adherence to treatment regimens.