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Date Published: 15/04/2023
Online Published: 15/04/2023
Abstract Views: 473
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DOI: https://doi.org/10.58490/ctump.2023i58.666
Issue
No. 58 (2023): HỘI NGHỊ KHOA HỌC QUỐC TẾ MỞ RỘNG LẦN THỨ II NĂM 2023
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Article
How to Cite
Dang , V. T., & Dang , V. T. (2023). THE EVALUATION OF THE RESULTS OF TAMSULOSIN IN THE MEDICAL EXPULSIVE TREATMENT OF DISTAL URETERAL STONES AT DA NANG HOSPITAL. Cantho Journal of Medicine and Pharmacy, 58, 1-5. https://doi.org/10.58490/ctump.2023i58.666

THE EVALUATION OF THE RESULTS OF TAMSULOSIN IN THE MEDICAL EXPULSIVE TREATMENT OF DISTAL URETERAL STONES AT DA NANG HOSPITAL

Van Thang Dang 1,, Van Thoi Dang 2
1 Da Nang Hospital
2 Da Nang University of Medical Technology and Pharmacy

Main Article Content

Abstract

Background: Ureteral stones is a common urological disease, and many studies have used tamsulosin to medical expulsive therapy for distal ureteral stones with high success rates. Objective: To evaluate of the results of tamsulosin in the Medical Expulsion Therapy for Distal Ureteral Stone. Materials and method: Patients with distal ureteral stones had stone size from 5 to 9mm, non-contrast computed tomography is used to diagnose ureteral stones, treated with Tamsulosin 0.4mg x1 tablet daily, re-examination after 2 weeks and 4 weeks to evaluate success by X-ray kidney, ureter and bladder, and abdominal ultrasound. Statistical analyses were performed using SPSS Statistics ver 20.0. Results: There were 45 patients with distal ureteral stones, mean age 48.10 ± 12.56, Male: 54.8%, female: 45.2%. The average stone size was 6.43 ± 1.33mm. After two weeks of treatment, the success rate was 71.1%, after 4 weeks it was 75.5%. Success in the group of stones with the size of 5-7mm was 62.2%, the group of stones with the size of 8-9mm was 13.3% and there was a statistically significant difference between the two groups, p < 0.05. Conclusion: The successful result after 4 weeks of treating distal ureteral stones with tamsulosin is 75.5%. The smaller the ureteral stones, the higher the success rate. Tamsulosin is effective in the treatment of distal ureteral stones.

Article Details

Keywords

Ureteral stones, tamsulosin, medical expulsion therapy ureteral stones

References

1. Campschroer T, Zhu Y, Duijvesz D, et al. (2014), Alpha-blockers as medical expulsive therapy for ureteral stones, Cochrane Database Syst Rev(4), pp. Cd008509.
2. Cui Y, Chen J, Zeng F, et al. (2019), Tamsulosin as a Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, J Urol. 201(5), pp. 950-955.
3. Furyk J S, Chu K, Banks C, et al. (2016), Distal Ureteric Stones and Tamsulosin: A Double-Blind, Placebo-Controlled, Randomized, Multicenter Trial, Ann Emerg Med. 67(1), pp. 86-95.e2.
4. Hollingsworth J M, Canales B K, Rogers M A, et al. (2016), Alpha blockers for treatment of ureteric stones: systematic review and meta-analysis, Bmj. 355, pp. i6112.
5. Moon Y J, Kim H W, Kim J B, et al. (2015), Distribution of ureteral stones and factors affecting their location and expulsion in patients with renal colic, Korean J Urol. 56(10), pp. 717-21.
6. Raison N, Ahmed K, Brunckhorst O, et al. (2017), Alpha blockers in the management of ureteric lithiasis: A meta-analysis, Int J Clin Pract. 71(1).pp. e12917.
7. Singh A, Alter H J and Littlepage A (2007), A systematic review of medical therapy to facilitate passage of ureteral calculi, Ann Emerg Med. 50(5), pp. 552-63.
8. Türk C, Neisius A, Seitz C, S et al. (2020), Eau Guidelines On Urolithiasis, European Association of Urology Pocket Guidelines, pp. 289-320.
9. Türk C, Petřík A, Sarica K, et al. (2016), EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis, Eur Urol. 69(3), pp. 468-74.
10. Wang R C, Smith-Bindman R, Whitaker E, et al. (2017), Effect of Tamsulosin on Stone Passage for Ureteral Stones: A Systematic Review and Meta-analysis, Ann Emerg Med. 69(3), pp. 353-361.e3.