TÌNH HÌNH SỬ DỤNG KHÁNG SINH HỢP LÝ VÀ MỘT SỐ YẾU TỐ LIÊN QUAN TRONG ĐIỀU TRỊ NỘI TRÚ TẠI BỆNH VIỆN BÌNH AN – KIÊN GIANG NĂM 2021

Abstract

Background: Currently, the situation of antibiotic resistance is always at an alarming level, the selection of appropriate antibiotics is a big challenge for health workers. Objectives: To determine the characteristics of antibiotic use, the rate of appropriate antibiotic use rates and to explore some related factors to inappropriate antibiotic use in inpatient treatment at Binh An - Kien Giang Hospital in 2021. Materials and methods: A cross-sectional descriptive study from 368 antibiotic-using medical records of inpatients at Binh An - Kien Giang Hospital in 2021. Investigating usage characteristics, assessment of appropriate antibiotic use according to guidelines of the Ministry of Health in 2015 and Vietnamese National Drug Formulary in 2018. Results: The most used antibiotics are β-lactams, accounting for 57.7%. There was 54.9% of cases with antibiotic combination. The rate of rational use of antibiotics was 71.7%. In which, the reasonable rates of antibiotic selection, dosage, dose interval, and de-escalation were 81.3%, 98.1%, 96.7%, and 85.4%, respectively. We found an association between inappropriate antibiotic use and gender, number of comorbidities, number of antibiotics switching times with p < 0.05. Conclusions: The reasonable rate of antibiotic use was 71.7%. It is necessary to step up the work of clinical pharmacy, implement management and intervention plans to ensure the rational use of antibiotics, improve the quality of treatment.