CLINICAL AND PARACLINICAL CHARACTERISTICS AND CLASSIFICATION OF MAXILLOFACIAL INFECTIONS ORIGINATING FROM MANDIBULAR MOLARS
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Abstract
Background: Maxillofacial infections originating from mandibular molars often progress rapidly and may spread extensively. Describing the clinical and paraclinical characteristics is essential for appropriate management. Objectives: To describe the clinical and paraclinical characteristics and to classify the severity of maxillofacial infections caused by mandibular molars. Materials and methods: An analytical cross-sectional study was conducted on 30 hospitalized patients diagnosed with maxillofacial infections secondary to mandibular molars from June 2025 to January 2026 at Tay Nguyen Regional General Hospital, Dak Lak. Variables included clinical features, hematological findings, microbiological results, imaging characteristics, and classification of infection severity. Results: A total of 30 patients were included, with a mean age of 50.6 ± 17.4 years, males and females were equally represented. Facial asymmetry was observed in 93.3% of cases and trismus in 46.7%, with no significant sex differences in clinical symptoms (p > 0.05). Females had a longer duration of symptoms than males (11.7 ± 5.3 vs. 8.9 ± 4.6 days, p = 0.048). The mean white blood cell count was 14.5 ± 5.1 G/L, with leukocytosis present in 86.7% of patients. Although the mean white blood cell count was higher in males than in females (15.8 ± 5.0 vs. 13.2 ± 4.9 G/L), the difference was not statistically significant (p = 0.167). Ultrasound findings most commonly showed abscess formation (53.3%), with no significant sex differences in imaging characteristics. Infection classification revealed that diffuse cellulitis accounted for 53.3% of cases, deep localized infection for 40.0%, and superficial localized infection for 6.7%. The proportion of diffuse infection was higher in males than in females (60.0% vs. 46.7%), but this difference was not statistically significant (p = 0.447). Conclusion: Maxillofacial infections caused by mandibular molars were predominantly diffuse and frequently associated with leukocytosis. No statistically significant sex-related differences were observed in infection severity or paraclinical characteristics, except for a longer duration of symptoms in females.
Keywords
Maxillofacial infection, mandibular molars, clinical characteristics, subclinical findings, cellulitis
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References
2. Kauffmann P., Cordesmeyer R., Tröltzsch M., Sömmer C., and Laskawi R. Deep neck infections: a single-center analysis of 63 cases. Med Oral Patol Oral Cir Bucal. 2017. 22(5), e536-e541, doi: 10.4317/medoral.21799.
3. Keswani E.S., and Venkateshwar G. Odontogenic maxillofacial space infections: A 5-year retrospective review in Navi Mumbai. J Maxillofac Oral Surg. 2019. 18(3), 345-353, doi: 10.1007/s12663-018-1152-x.
4. Moghimi M., Baart J.A., Karagozoglu K.H., and Forouzanfar T. Spread of odontogenic infections: A retrospective analysis and review of the literature. Quintessence Int. 2013. 44(4), 351-361, doi: 10.3290/j.qi.a29150.
5. Nguyễn Tiến Thành, Phạm Như Hải và Lê Ngọc Tuyến. Kết quả điều trị bệnh nhân viêm nhiễm vùng hàm mặt tại Bệnh viện Răng Hàm Mặt Trung ương Hà Nội năm 2023. Tạp chí Y học Việt Nam. 2024. 539(2), 1-5, doi: 10.51298/vmj.v539i2.9780.
6. Gadicherla S., Manglani K., Pentapati K.C., Kudva A., Aramanadka C., et al. Profile of patients with maxillofacial space infections and associated risk factors. Sci World J. 2024. 2024, 9304671, doi: 10.1155/2024/9304671.
7. Jevon P., Abdelrahman A., and Pigadas N. Management of odontogenic infections and sepsis: An update. Br Dent J. 2020. 229(6), 363-370, https://doi.org/10.1038/s41415-020-2114-5.
8. Đậu Đức Thành, Phan Thị Thục Anh, Đậu Lệ Thủy, Nguyễn Việt Anh, Đặng Đình Quang và cộng sự. Đặc điểm lâm sàng, cận lâm sàng bệnh nhân viêm nhiễm vùng hàm mặt do răng tại Bệnh viện Hữu nghị Đa khoa Nghệ An năm 2022-2024. Tạp chí Y học Cộng đồng. 2025. 66(CD9), 63-68, doi: 10.52163/yhc.v66iCD9.2680.
9. Hupp J.R., Tucker M.R., and Ellis E. Contemporary Oral and Maxillofacial Surgery. 7th ed. Elsevier. 2019.
10. Kamiński B., Błochowiak K., Kołomański K., Sikora M., Karwan S., et al. Oral and maxillofacial infections-a bacterial and clinical cross-section. J Clin Med. 2022. 11(10), 2731, doi: 10.3390/jcm11102731.
11. Nguyễn Thanh Quang và Trương Nhựt Khuê. Nghiên cứu đặc điểm lâm sàng, cận lâm sàng ở bệnh nhân viêm nhiễm vùng hàm mặt do răng tại Bệnh viện Mắt - Răng Hàm Mặt Cần Thơ năm 2015-2017. Tạp chí Y học thực hành. 2017. 8, 248-251.
12. Robertson D., and Smith A.J. The microbiology of the acute dental abscess. J Med Microbiol. 2009, 58(Pt 2), 155-162, doi: 10.1099/jmm.0.003517-0.
13. Siqueira J.F. Jr, and Rôças I.N. Microbiology and treatment of acute apical abscesses. Clin Microbiol Rev. 2013. 26(2), 255-273, https://doi.org/10.1128/CMR.00082-12.
14. Stefanopoulos P.K., and Kolokotronis A.E. The clinical significance of anaerobic bacteria in acute orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004. 98(4), 398-408, doi: 10.1016/j.tripleo.2004.01.016.