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Issue: No. 100 (2026)
Section: Article
DOI: 10.58490/ctjump.2026i100.4731
Date Published: 25/07/2026
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Huynh, T. K., Duong, T. T. V., Ngo, P. D., Lam, T. H., Tran, G. H., Huynh, T. H., Tu, T. T., & Bui, Q. N. (2026). 30-DAY MORTALITY AND THE PROGNOSTIC UTILITY OF CLINICAL SCORING SYSTEMS IN HOSPITALIZED PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA. Cantho Journal of Medicine and Pharmacy, 100, 167-174. https://doi.org/10.58490/ctjump.2026i100.4731

30-DAY MORTALITY AND THE PROGNOSTIC UTILITY OF CLINICAL SCORING SYSTEMS IN HOSPITALIZED PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA

Truong Khanh Huynh1, , Thi Thanh Van Duong1, Phuong Dung Ngo1, Truong Hung Lam1, Gia Han Tran1, Thanh Huy Huynh1, Thien Thanh Tu1, Quoc Nhan Bui1,
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Community-acquired pneumonia is a leading cause of hospitalization and mortality worldwide. Early identification of mortality risk at admission helps optimize treatment strategies and stratification. Objectives: To determine the 30-day mortality rate and evaluate the prognostic value of the CURB-65, PSI, qSOFA, and NEWS2 scoring systems in patients hospitalized with community-acquired pneumonia. Materials and methods: A prospective, longitudinal observational study was conducted on 140 patients diagnosed with community-acquired pneumonia and admitted to Can Tho Central General Hospital and Can Tho University of Medicine and Pharmacy Hospital from June 2025 to January 2026. The CURB-65, PSI, qSOFA, and NEWS2 scores were calculated at admission. Patients were followed for 30-day mortality outcomes. Results: Among a total of 140 hospitalized patients with community-acquired pneumonia, 36 cases (25.7%) died within 30 days. Multivariate logistic regression analysis showed that septic shock was an independent risk factor associated with mortality (OR = 35.0; 95% CI: 10.55 – 116.09; p < 0.001). ROC curve analysis indicated that the NEWS2 score had the best prognostic value for mortality, with an area under the curve (AUC) of 0.66 (p = 0.004). At the optimal cut-off value of  ≥ 7 points, the sensitivity and specificity were 80.6% and 52.9%, respectively. The CURB-65, PSI, and qSOFA scores did not yield statistically significant prognostic values. Conclusions: Septic shock is an independent risk factor for mortality. The NEWS2 score demonstrates superior prognostic value for mortality compared to CURB-65, PSI, and qSOFA, facilitating effective risk stratification upon hospital admission. 

Keywords

Community-acquired pneumonia, 30-day mortality, CURB-65, PSI, qSOFA, NEWS2

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