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Issue: No. 96 (2026): HỘI NGHỊ THƯỜNG NIÊN HỌC VIÊN, SINH VIÊN NGHIÊN CỨU KHOA HỌC LẦN THỨ VI NĂM 2026
Section: Article
DOI: 10.58490/ctjump.2026i96.4597
Date Published: 25/03/2026
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Duong, M. L., Pham, T. D., Nguyen, T. T. A., & Tran, T. T. (2026). DIAGNOSTIC VALUE OF THE URIC ACID/ALBUMIN AND URIC ACID/ CREATININE RATIOS IN ASSESSING THE SEVERITY OF PREECLAMPSIA. Cantho Journal of Medicine and Pharmacy, 96, 145-151. https://doi.org/10.58490/ctjump.2026i96.4597

DIAGNOSTIC VALUE OF THE URIC ACID/ALBUMIN AND URIC ACID/ CREATININE RATIOS IN ASSESSING THE SEVERITY OF PREECLAMPSIA

My Linh Duong1, , Thanh Duong Pham2, Thuy Thuy Ai Nguyen3, Thanh Trung Tran4
1 Can Tho University of Medicine and Pharmacy
2 Thong Nhat General Hospital
3 Can Tho Gynecology Obstetrics Hospital
4 Dinh Quan Regional General Hospital

Main Article Content

Abstract

Background: Preeclampsia is one of the most serious complications of pregnancy, significantly affecting the health of both the mother and the fetus. Blood biochemical ratios such as the uric acid/albumin ratio and the uric acid/creatinine ratio may provide more accurate prediction of preeclampsia severity. Objective: To determine the diagnostic value of the uric acid/albumin ratio and the uric acid/creatinine ratio in assessing the severity of preeclampsia among pregnant women in Dong Nai Province. Materials and method: A cross-sectional descriptive study was conducted among 60 pregnant women attending hospitals in Dong Nai Province. Pregnant women diagnosed with preeclampsia were evaluated for disease severity. The diagnostic performance of the uric acid/albumin ratio and the uric acid/creatinine ratio in identifying severe preeclampsia was analyzed. Results: The cutoff value of the uric acid/albumin ratio for diagnosing severe preeclampsia was 1.75 with sensitivity, specificity, positive predictive value, and negative predictive value of 67%, 70.4%, 63.3%, and 73.3%, respectively. The cutoff value of the uric acid/creatinine ratio for diagnosing severe preeclampsia was 6.78, with a sensitivity of 64%, specificity of 74.1%, positive predictive value of 62.5%, and negative predictive value of 75%. Both ratios demonstrated diagnostic value in assessing the severity of preeclampsia (p < 0.05). Conclusion: The uric acid/albumin ratio and the uric acid/creatinine ratio are valuable indicators for diagnosing the severity of preeclampsia and should be encouraged for clinical use. 

Keywords

Preeclampsia, uric acid/albumin ratio, uric acid/creatinine ratio

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