ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ VIÊM MŨI XOANG MẠN TÍNH CÓ POLYP MŨI BẰNG LIỆU PHÁP METHYLPREDNISOLONE TOÀN THÂN KẾT HỢP XỊT MOMETASONE FUROATE TẠI CHỖ TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2024-2026

Abstract

Background: Chronic rhinosinusitis is one of the most common diseases in ENT. Nasal polyps are the consequence of prolonged mucosal edema caused by various factors, most commonly chronic rhinosinusitis, a condition referred to as chronic rhinosinusitis with nasal polyps (CRSwNP). Objectives: To describe the clinical, paraclinical characteristics and evaluate treatment outcomes of CRSwNP treated with systemic Methylprednisolone combined with topical intranasal Mometasone furoate at Can Tho University of Medicine and Pharmacy Hospital during the period 2024-2026. Materials and methods: A descriptive case series study including 30 patients diagnosed with chronic rhinosinusitis with nasal polyps at Can Tho University of Medicine and Pharmacy Hospital from 2024 to 2026. Results: Chronic rhinosinusitis with nasal polyps was most commonly observed in the 31-45 year age group (46.7%). Regarding clinical characteristics, the most common clinical symptoms in this disease group were rhinorrhea and nasal obstruction, with prevalence rates of 93.3% and 80%, respectively. Concerning paraclinical features, most patients presented with grade I middle meatal polyps (60%). Regarding treatment, the mean duration of treatment was 21.63±9.368 days. Overall, 86.7% of patients responded to steroids therapy after 4 weeks of treatment. Conclusion: The majority of patients with chronic rhinosinusitis with nasal polyps were aged between 31 and 45 years. The two most common clinical symptoms were nasal obstruction and rhinorrhea. Most patients had grade I middle meatal nasal polyps, the mean duration of treatment was 21.63±9.368 days and 86.7% of patients showed a favorable response to steroid treatment.