EARLY OUTCOMES OF PERCUTANEOUS TRANSHEPATIC GALLBLADDER DRAINAGE IN PATIENTS WITH GRADE III ACUTE CHOLECYSTITIS ACCORDING TO TOKYO GUIDELINES 2018 AT CAN THO GENERAL HOSPITAL

Thanh Tri Le1, , Thanh Tin Le1, Cam Hong Huynh1, Nguyen Minh Hien Bach1, Thanh Thuy Phan1, Anh Vu Doan1, Van Phu La2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho General Hospital

Main Article Content

Abstract

Background: Percutaneous transhepatic gallbladder drainage is an effective decompression method for the gallbladder, indicated in patients with acute cholecystitis who are at high surgical risk. Objectives: To assess the success rate of percutaneous transhepatic gallbladder drainage in patients with Grade III acute cholecystitis according to the Tokyo Guidelines 2018 at Can Tho General Hospital. The evaluation covers clinical and laboratory characteristics before and after the procedure, and surgical outcomes are assessed using the Clavien-Dindo classification of surgical complications. Materials and methods: A prospective descriptive study combined with retrospective analysis was conducted on 30 patients diagnosed with grade III acute cholecystitis treated with percutaneous transhepatic gallbladder drainage. Clinical signs, laboratory parameters, procedural data (procedure time, success rate, fluid characteristics), and post-procedure complications were statistically analyzed (p ≤ 0.05). Results: The mean age was 73.83±10.73 years with 57% male. Regarding surgical risk, 83.33% were classified as ASA III, while the remaining 16.67% were classified as ASA IV. The percutaneous transhepatic gallbladder drainage success rate was 100%. According to the ClavienDindo classification, 7 cases (23.33%) had postoperative complications: four patients (13.33%) experienced Grade III complications, two patients (6.67%) experienced Grade IV complications, and one patient (3.33%) experienced a Grade V complication. Conclusion: Percutaneous transhepatic gallbladder drainage is an effective method for gallbladder decompression, with high success rates in symptom improvement for high-risk cholecystectomy cases. 

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References

1. Yokoe M., Takada T., Strasberg S.M., Solomkin J.S., Mayumi T. et al. TG13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2013. 20(1), 35-46, doi: 10.1007/s00534-012-0568-9.
2. Mori Y., Itoi T., Baron T.H., Takada T., Strasberg S.M. et al. Tokyo Guidelines 2018: management strategies for gallbladder drainage in patients with acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2018. 25(1), 87-95, doi: 10.1002/jhbp.504.
3. Patel I.J., Davidson J.C., Nikolic B., Salazar G.M., Schwartzberg M.S. et al. Consensus guidelines for periprocedural management of coagulation status and hemostasis risk in percutaneous image-guided interventions. J Vasc Interv Radiol. 2012. 23(6), 727-736, doi: 10.1016/j.jvir.2012.02.012.
4. Bozic D., Ardalic Z., Mestrovic A., Bilandzic Ivisic J., Alicic D. et al. Assessment of Gallbladder Drainage Methods in the Treatment of Acute Cholecystitis: A Literature Review. Medicina. 2024. 60(1), 5.
5. Nve E., Badia J.M., Amillo-Zaragüeta M., Juvany M., Mourelo-Fariña M. et al. Early Management of Severe Biliary Infection in the Era of the Tokyo Guidelines. J Clin Med. 2023. 12(14), doi: 10.3390/jcm12144711.
6. Ábrahám S., Tóth I., Benkő R., Matuz M., Kovács G. et al. Surgical outcome of percutaneous transhepatic gallbladder drainage in acute cholecystitis: Ten years' experience at a tertiary care centre. Surg Endosc. 2022. 36(5), 2850-2860, 10.1007/s00464-021-08573-0.
7. Abe K., Suzuki K., Yahagi M., Murata T., Sako H. et al. The Efficacy of PTGBD for Acute Cholecystitis Based on the Tokyo Guidelines 2018. World J Surg. 2019. 43(11), 2789-2796, doi: 10.1007/s00268-019-05117-5.
8. Mishima K., Fujiyama Y., Wakabayashi T., Igarashi K., Ozaki T. et al. Early laparoscopic cholecystectomy for acute cholecystitis following the Tokyo Guidelines 2018: a prospective single-center study of 201 consecutive cases. Surg Endosc. 2023. 37(8), 6051-6061, doi: 10.1007/s00464-023-10094-x.
9. Gao W., Zheng J., Bai J.G. Han Z. Effect of surgical timing on postoperative outcomes in patients with acute cholecystitis after delayed percutaneous transhepatic gallbladder drainage. World J Gastrointest Surg. 2024. 16(11), 3445-3452, doi: 10.4240/wjgs.v16.i11.3445.
10. Nguyễn Thành Nhân. Kết quả sớm của dẫn lưu túi mật xuyên gan qua da trong điều trị viêm túi mật cấp do sỏi. Đại học Y Dược Thành phố Hồ Chí Minh. 2017. 99.
11. Lee O., Shin Y.C., Ryu Y., Yoon S.J., Kim H. et al. Comparison between percutaneous transhepatic gallbladder drainage and upfront laparoscopic cholecystectomy in patients with moderate-to-severe acute cholecystitis: a propensity score-matched analysis. Ann Surg Treat Res. 2023. 105(5), 310-318, 10.4174/astr.2023.105.5.310.