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Date Published: 17/12/2022
Online Published: 17/01/2023
Abstract Views: 666
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DOI: https://doi.org/10.58490/ctump.2022i54.368
Issue
No. 54 (2022)
Section
Article
How to Cite
Nguyen , V. L., & Tran, N. D. (2023). STUDY ON THE TREATMENT COMPLIANCE, ASSOCIATED FACTORS AND RESULTS OF PRE-EXPOSURE PROPHYLAXIS FOR HIGH-RISK PATIENTS’ HIV EXPOSURE AT BA RIA – VUNG TAU PROVINCE IN 2021-2022. Cantho Journal of Medicine and Pharmacy, 54, 124-131. https://doi.org/10.58490/ctump.2022i54.368

STUDY ON THE TREATMENT COMPLIANCE, ASSOCIATED FACTORS AND RESULTS OF PRE-EXPOSURE PROPHYLAXIS FOR HIGH-RISK PATIENTS’ HIV EXPOSURE AT BA RIA – VUNG TAU PROVINCE IN 2021-2022

Van Len Nguyen 1,, Ngoc Dung Tran2
1 Ba Ria – Vung Tau provincial Center for Disease Control
2 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: In 2017, Viet Nam piloted Pre-Exposure Prophylaxis (PrEP). There were only 03 new HIV infections in 18 months. Objectives: To determine the rate of adherence to PrEP, to identify some associated factors to adherence to PrEP, and to evaluate the results of PrEP in patients with behaviors at risk of HIV infection. Materials and methods: People who had behaviors at risk of HIV infection registered for PrEP treatment in Ba Ria - Vung Tau province from July 2019 to December 2020. They are followed until June 2021. The method was a crosssectional study with analysis. The whole sampling method was used. Results: Out of 256 people, 52.7% were male; the age group 20-39 accounted for 80.5%; self-employed accounted for 46.9%; men who have sex with men accounted for 45.7%. The rate of subjects who adhered to PrEP treatment was 47.7%. Using multivariable logistic regression analysis, several factors associated with adherence to PrEP treatment were found, including age, occupation, having sex with HIVinfected persons with untreated or unknown infection status, and not using condoms during sex. Results showed that 46.1% of subjects responded to PrEP and one subject was newly infected with HIV. Conclusion: The rate of adherence to HIV pre-exposure prophylaxis is 47.7%. Some factors related to the adherence of subjects are age, occupation, sexual behavior with HIV-infected people who have not been treated or have unknown HIV status, and not using condoms during sex. There was one person infected with HIV, occupying 0.4%. It is recommended to support treatment adherence for those under the age of 20; a freelance workforce; develop a peer network; guiding combine PrEP treatment and the maintenance of condom use during sex to prevent HIV and sexually transmitted infections.

Article Details

Keywords

HIV Pre-Exposure Prophylaxis, patients with high risk

References

1. Green, K. E., Nguyen, L. H., Phan, H. T. T., et al. (2021), "Prepped for PrEP? Acceptability, continuation and adherence among men who have sex with men and transgender women enrolled as part of Vietnam's first pre-exposure prophylaxis program", Sex Health. 18(1), pp. 104-115.
2. Hillis, A., Germain, J., Hope, V., et al. (2020), "Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among Men Who Have Sex with Men (MSM): A Scoping Review on PrEP Service Delivery and Programming", AIDS Behav. 24(11), pp. 3056-3070.
3. Hoornenborg, E., Coyer, L., Achterbergh, R. C. A., et al. (2019), "Sexual behaviour and incidence of HIV and sexually transmitted infections among men who have sex with men using daily and event-driven pre-exposure prophylaxis in AMPrEP: 2 year results from a demonstration study", Lancet HIV. 6(7), pp. e447-e455.
4. Laurent, C., Keita, B. D., Yaya, I., et al. (2021), "HIV pre-exposure prophylaxis for men who have sex with men in west Africa: a multicountry demonstration study", Lancet HIV. 8(7), pp. e420-e428.
5. Olsen, T., Lally-Montgomery, Z., Kelsberg, G., et al. (2021), "Is event-driven PrEP dosing for HIV as effective as daily dosing?", J Fam Pract. 70(5), pp. 253-255.
6. Pasipanodya, E. C., Jain, S., Sun, X., et al. (2018), "Trajectories and Predictors of Longitudinal Preexposure Prophylaxis Adherence Among Men Who Have Sex With Men", J Infect Dis. 218(10), pp. 1551-1559.
7. Qu, D., Zhong, X., Xiao, G., et al. (2018), "Adherence to pre-exposure prophylaxis among men who have sex with men: A prospective cohort study", Int J Infect Dis. 75, pp. 52-59.
8. Seekaew, P., Nguyen, E., Sungsing, T., et al. (2019), "Correlates of nonadherence to key population-led HIV pre-exposure prophylaxis services among Thai men who have sex with men and transgender women", BMC Public Health. 19(1), pp. 328.
9. Tassi, M. F., Laurent, E., Gras, G., et al. (2021), "PrEP monitoring and HIV incidence after PrEP initiation in France: 2016-18 nationwide cohort study", J Antimicrob Chemother. 76(11), pp. 3002-3008.
10. Wahome, E. W., Graham, S.M., Thiong'o, A. N., et al. (2020), "PrEP uptake and adherence in relation to HIV-1 incidence among Kenyan men who have sex with men", EClinicalMedicine. 26, pp. 100541.
11. Yun, K., Xu, J., Zhang, J., et al. (2018), "Female and younger subjects have lower adherence in PrEP trials: a meta-analysis with implications for the uptake of PrEP service to prevent HIV", Sex Transm Infect. 94(3), pp. 163-168.