ĐIỀU TRỊ CHỨNG NHUYỄN SỤN XƯƠNG BÁNH CHÈ DO TẬP LUYỆN THỂ THAO BẰNG LIỆU PHÁP HUYẾT TƯƠNG GIÀU TIỂU CẦU TỰ THÂN

Abstract

Background: Patellar chondromalacia refers to cartilage damage in the patella, leading to pain and restricted knee joint mobility, particularly in young individuals engaged in sports activities. Current treatments primarily provide temporary pain relief without restoring cartilage integrity. Platelet-rich plasma (PRP) has shown promising results in multiple studies. Objective: To evaluate the pain relief and functional improvement effects of Platelet-rich plasma therapy in in treating patellar chondromalacia caused by physical exercise. Materials and methods: This prospective clinical trial included 19 patients (26 affected knees), aged 18 to < 40, who engaged in systematic sports training and had cartilage damage of grade 2 or higher, with prior treatment failure. The treatment protocol consisted of three intra-articular knee injections, administered biweekly. Outcomes were evaluated using VAS and WOMAC scores at baseline (T₀), two weeks post-treatment (T₁), and eight weeks post-treatment (T₂). Data were analyzed using Excel, with statistical testing via t-test and ANOVA at a significance level of p < 0.05. Results: At two week and eight weeks posttreatment, VAS scores decreased from 6.89 to 5.0 and 1.89, respectively. WOMAC pain scores declined from 15.0 to 10.53 and 2.63, WOMAC stiffness scores from 2.89 to 1.63 and 0.53, and WOMAC function scores from 33.37 to 21.84 and 9.95. All improvements were statistically significant (p < 0.0001). Conclusion: PRP therapy significantly reduces pain, alleviates stiffness, and enhances knee joint function. It represents an effective conservative treatment for patellar chondromalacia, particularly in patients unresponsive to conventional therapies. However, the study is limited by its small sample size and short follow-up period.