KHẢO SÁT HOẠT TÍNH KHÁNG OXY HÓA VÀ KHÁNG KHUẨN CỦA CAO CHIẾT QUẢ CÂY MẮM LƯỠI ĐỒNG (Avicennia officinalis L.)

Abstract

 Background: Studies in recent years have found that the methanol fruit extract of Avicennia officinalis L. had antibacterial activity. However, studies on the fruit extract of Avicennia officinalis L. in the world and in Vietnam are still limited. Objective: To contribute to the evaluation of the antioxidant and antibacterial activities of Avicennia officinalis L. fruit extract collected at Ca Mau province. Materials and methods: Avicennia officinalis L. fruit was extracted with methanol solvent using the ultrasound-assisted extraction, and its antioxidant activity was evaluated by the 2,2diphenyl-1-picrylhydrazyl (DPPH) free radical efficiency and the antibacterial activity was evaluated by the disc diffusion with 3 bacterial strains Staphylococcus aureus, Escherichia coli, and Psedomonas aeruginosa. Results: The results of the study showed that the methanol extract of Avicennia officinalis L. fruit had antioxidant potential on the DPPH free radical with EC₅₀ of 181.6 μg/mL. The antibacterial potential on three common bacterial strains Staphylococcus aureus, Escherichia coli, Psedomonas aeruginosa with antibacterial diameters at a concentration of 10 mg/mL was (18.6; 18.0 and 13.8 mm, respectively). The antibacterial activity of the extract of the

Avicennia officinalis L. fruit was equivalent to that of Tetracycline at a concentration of 62.5 μg/mL against the Psedomonas aeruginosa strain. Conclusion: The study contributed to providing information on the potential antioxidant and antibacterial activity of the Avicennia officinalis L. fruit collected at Ca Mau province, Vietnam.