Article Sidebar
Views PDF: 79
SPONTANEOUS INTRACEREBRAL HEMORRHAGE UPDATE ON TREATMENT IN CLINICAL PRACTICE
Main Article Content
Abstract
Spontaneous (non-traumatic) intracerebral hemorrhage is a type of acute stroke. The disease has many complications, many disabilities and causes high mortality. During the past decades, Guidelines for the treatment of patients with spontaneous intracerebral hemorrhage have been published. However, the treatments in these guidelines are not really effective and do not have enough evidence. To improve treatment outcomes and reduce mortality, more new evidence is needed and patients need to be treated early and comprehensively with more effective treatments. Recently, there has been significant evidence from clinical trials on the treatment of spontaneous intracerebral hemorrhage. Based on this evidence, new guidelines have been published. Currently, the main treatments in the acute phase include: controlling the spread of hematoma, early surgery, preventing complications and secondary brain damage. Updating advances in the treatment of this disease through reviewing and analyzing information from literature is very important and necessary for clinicians.
Article Details
Keywords
Update, treatment, spontaneous intracerebral hemorrhage
References
2. Murthy SB. Emergent management of intracerebral hemorrhage. CONTINUUM: Lifelong Learning in Neurology. 2024. 30, 641-661.
3. Seiffge D.J., Anderson C.S. Treatment for intracerebral hemorrhage: Dawn of a new era. International Journal of Stroke. 2024. 19, 482-489.
4. Li Z., Khan S., Liu Y., Wei R., Yong V.W., et al. Therapeutic strategies for intracerebral hemorrhage. Frontiers in Neurology. 2022. 13, 1032343.
5. Magid-Bernstein J., Girard R., Polster S., Srinath A., Romanos S., et al. Cerebral hemorrhage: pathophysiology, treatment, and future directions. Circulation research. 2022. 130, 1204-1229.
6. Ruff I.M., de Havenon A., Bergman D.L., Dugue R., Frontera J.A., et al. 2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association. Stroke. 2024.
7. Li G., Lin Y., Yang J., Anderson C.S., Chen C., et al. Intensive ambulance-delivered bloodpressure reduction in hyperacute stroke. New England Journal of Medicine. 2024.
8. Ma L., Hu X., Song L., Chen X., Ouyang M., et al. The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial. The Lancet. 2023. 402, 27-40.
9. Bhalla A., Clark L., Fisher R., James M. The new national clinical guideline for stroke: an opportunity to transform stroke care. Clinical Medicine. 2024. 24, 100025.
10. Brunström M., Burnier M., Grassi G., Januszewicz A., Muiesan M.L., et al. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension. Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). Journal of Hypertension. 2023. 41, 1874-2071.
11. Balali P., Hart R.G., Smith E.E., Saad F., Colorado P., et al. Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFICSTROKE randomized trial. International Journal of Stroke. 2023, 17474930231216339.
12. Pradilla G., Ratcliff J.J., Hall A.J., Saville B.R., Allen J.W., et al. Trial of early minimally invasive removal of intracerebral hemorrhage. New England Journal of Medicine. 2024. 390, 1277-1289.