STUDY THE SITUATION AND ROLE OF RETICULOCYTE HEMOGLOBIN INDEXES TO DIAGNOSE IRON DEFICIENCY ANEMIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE WITHOUT RENAL REPLACEMENT TREATEMNT AT KIEN GIANG PROVINCE GENERAL HOSPITAL IN 2023 - 2024
Main Article Content
Abstract
Background: Iron deficiency anemia in patient with chronic kidney disease often is due to renal hematopoietic dysfunction, it often increases in stages 3-5, which are risk factors for death of patients. Objectives: To determine the rate of iron deficiency anemia, some related factors and the value of reticulocyte hemoglobin index to diagnosing iron deficiency anemia of patients with chronic kidney disease without renal replacement treatment at Kien Giang Province General Hospital. Materials and methods: A cross-sectional study was conducted on 100 patients who diagnosed chronic kidney disease according to the American Society of Nephrology in 2017. Results: The proportion of women was 61%. Average age was 60.6 years old; 4 stage was 39.0%; G5 stage was 22.0% and there were no cases of consolidation in 1 and 2 stages. The percentage of iron deficiency anemia in kidney disease patients was 29.0%. Patients in stage 5 had get higher risk of IDA than those in stage 4 (OR: 3.08 and p < 0.05); and it was higher than the group with disease in stage 3 (OR: 5.86 and p < 0.01). The value of iron deficiency anemia of patient with chronic kidney disease was AUC (0.793) with p < 0.001; Cut-off: 28.05; Sensitivity (82.1%); Specificity (72.2%) and LR+ (3.1). Conclusion: Through a study of 100 chronic kidney patients without renal replacement treatment, the rate of iron deficiency anemia was high and related to the stage of the disease. CHr had a diagnostic cost of iron deficiency anemia with cut-off of 28.05pg, but the likelihood of diagnosing the disease was low.
Keywords
Iron deficiency, anemia, chronic kidney disease, reticulocyte
Article Details
References
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