NGHIÊN CỨU TÌNH HÌNH, MỘT SỐ YẾU TỐ NGUY CƠ LOÃNG XƯƠNG Ở PHỤ NỮ TRÊN 50 TUỔI THỪA CÂN, BÉO PHÌ TẠI BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ VÀ BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2022-2024

Abstract

  Background: Obesity and osteoporosis are two diseases whose pathogenesis originates from multipotent mesenchymal stem cells. The aim of study was estimated factors associated with osteoporosis in overweight and obesity women over 50 years old, screen out high-risk cases for early diagnosis and treatment which minimize sequelae caused by osteoporosis. Objectives: To determine bone mineral density (BMD), the prevalence of osteoporosis and indentified risk factors for osteoporosis in overweight and obese womens over 50 years old Materials and methods: A cross-sectional study was conducted on 129 overweight and obesity womens over 50 years old at Can Tho Central General Hospital and Can Tho University of Medicine and Pharmacy Hospital from 2/2023 to 04/2024. Each patient has to fill out a prepared questionnaire, bone densitometry at two of their lumbar vertebrae and the neck of their femur by DEXA for bone density assessment Results: 51.1% had overweight and 48.9% had osteopenia. The prevalence of osteoporosis in the femoral neck was 27.9% and in lumbar spine was 40.3%. BMD of obesity womens was higher than overweight (p<0.05). BMD of the over 60 years old group was lower than the 51 to 60 years old group (p<0.01). Osteoporosis in the lumbar spine showed an association with age (p<0.05), overweight (p<0.05), physical activity (p<0.05), time of menopause (p<0.05) and number of children (p<0.05). Osteoporosis in the femoral neck showed an assocation with age (p<0.05). Conclusions: The overweight group had a lower average bone density than the obese group at two locations: the femoral neck and the lumbar spine., but it had a higher rate of osteoporosis in the lumbar spine than the obese group.