ASSESSMENT OF BACTERIAL PROFILES AND ANTIBIOTIC RESISTANCE IN PATIENTS WITH TYPE 2 DIABETES AND NOSOCOMIAL PNEUMONIA AT CANTHO GENERAL HOSPITAL IN 2022

Xuan Tra Bui 1, Hoang Thuy Tien Nguyen2, Huy Kien Bui 3, Ngoc Tran Luu 2, Thi Nhu Ngoc Tran 4,
1 1. Can Tho General Hospital
2 Can Tho General Hospital
3 1.Can Tho General Hospital
4 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Nosocomial pneumonia ranks second in hospital-acquired infections, increasing costs and burden of disease. Patients with type 2 diabetes are susceptible to many infections including pneumonia and are at high risk of developing nosocomial pneumonia. Objectives: 1) To survey on the rate of bacteria causing hospital-acquired pneumonia in patients with type 2 diabetes. 2) To survey on antibiotic resistance rates in some bacteria causing hospitalacquired pneumonia in patients with type 2 diabetes. Materials and method: The study was case series, retrospective and analytical. Sampling is based on hospital admission records from January 2020 to September 2022, the method sampling is convenience sampling. Results: Gram-negative bacteria accounted for the majority (97.4%). The three most common bacteria were Acinetobacter baumannii (36.8%), Klebsiella pneumoniae (36.8%), and Pseudomonas aeruginosa (13.2%). Except for Colistin (sensitive 100.0%), Gram-negative bacteria are highly resistant to Cephalosporin III and Fluroquinolone groups in most of the remaining antibiotics. Acinetobacter baumannii is almost completely resistant to antibiotics, except colistin (100.0% sensitive). Klebsiella pneumoniae and Pseudomonas aeruginosa were highly resistant to many antibiotics except colistin (sensitivity 100.0%). Conclusion: The three most common bacteria in diabetic patients with hospital-acquired pneumonia include Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The rate of Gram-negative bacteria resistant to antibiotics is very high but still sensitive to Colistin.

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References

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