Article Sidebar

PDF
Date Published: 25/04/2024
Online Published: 25/04/2024
Abstract Views: 107
Views PDF: 74
DOI: https://doi.org/10.58490/ctump.2024i73.2546
Issue
No. 73 (2024)
Section
Article
How to Cite
Nguyen, T. K. O., & Nguyen, N. R. (2024). CLINICAL CHARACTERISTICS AND RISK FACTORS FOR ANEMIA IN CHILDREN INFECTED WITH HELICOBACTER PYLORI AT CAN THO CHILDREN’S HOSPITAL. Cantho Journal of Medicine and Pharmacy, 73, 173-179. https://doi.org/10.58490/ctump.2024i73.2546

CLINICAL CHARACTERISTICS AND RISK FACTORS FOR ANEMIA IN CHILDREN INFECTED WITH HELICOBACTER PYLORI AT CAN THO CHILDREN'S HOSPITAL

Thi Kieu Oanh Nguyen1,, Ngoc Rang Nguyen1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Backgroud: Anemia is a common consequence in children infected with Helicobacter pylori (Hp). Risk factors for anemia in Hp-infected children are controversial. Objectives: To describe clinical and characteristics and determine the prevalence and associated factors to anemia in Hpinfected children at Can Tho Children's Hospital. Materials and methods: A cross-sectional descriptive study of all children between the ages of 6 and 16 diagnosed with Hp infection by histopathology and urease test at the Department of Gastroenterology at Can Tho Children's Hospital. Results: There were 92 Hp-infected children in this study, of which 58 were females (63%), mean age was 10.5± 2.7 years. The prevalence of anemia was 25%. Specific clinical signs of the Hp infection group with anemia included: anorexia (26.1%), vomiting (78.1%), dizziness (34.8%), conjunctival pallor (78.3%), pale skin (69.6%), melena (39.1%), and hematemesis (17.4%). The older age group (11-16 years old) was a risk factor for anemia (OR=4.56; 1.41-12.7), iron supplementation (OR=0.13; 0.02-0, 62) was protective factors. Conclusion: The prevalence of anemia in Hp-infected children is relatively high. In children with Hp and anemia, clinical signs are often nonspecific. The risk factors for anemia in Hp-infected children are old age group (>11 years old), no iron supplementation and vitamin C.

Article Details

Keywords

Anemia, Helicobacter pylori, Hp-infected

References

1. Hooi, J.K., et al., Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis. Gastroenterology. 2017. 153(2), 420-429, doi: 10.1053/j.gastro.2017.04.022.
2. Yuan, C., et al., The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis. The Lancet Child & Adolescent Health. 2022. 6(3), 185-194, doi: 10.1016/S2352-4642(21)00400-4.
3. Che, T.H., et al., High prevalence of helicobacter pylori infection among school-aged children in Ho Chi Minh City, Vietnam. International journal of public health. 2022. 67, 1605354, doi: 10.3389/ijph.2022.1605354.
4. Lê Thọ, Nghiên cứu đặc điểm dịch tễ học nhiễm Helicobacter pylori ở trẻ em vùng Tây Nguyên, Việt Nam. 2021.
5. Dao, L.V., et al., Helicobacter pylori infection and eradication outcomes among Vietnamese patients in the same households: Findings from a non-randomized study. Plos one. 2021. 16(11), e0260454, doi: 10.1371/journal.pone.0260454.
6. Choe, Y.H., S.K. Kim, and Y.C. Hong, Helicobacter pylori infection with iron deficiency anaemia and subnormal growth at puberty. Archives of Disease in Childhood. 2000. 82(2), 13640, doi: 10.1136/adc.82.2.136.
7. Baggett, H.C., et al., Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in Alaska. Pediatrics. 2006. 117(3), e396-404, doi: 10.1542/peds.2005-1129.
8. Murphy, J., Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity. Vitamin and Mineral Nutrition Information System. Geneva: World Health Organization. 2011.
9. Programme, W.F., Food Consumption Score Nutritional Quality Analysis Guidelines (FCS-N). 2015, United Nations World Food Programme, Food Security Analysis (VAM) Rome, Italy.
10. Kawakami, E., et al., Clinical and histological features of duodenal ulcer in children and adolescents. Jornal de pediatria, 2004. 80, 321-325.
11. Nguyễn Thị Kim Loan and T.T.T. Tâm, Đặc điểm xuất huyết tiêu hóa ở trẻ viêm loét dạ dày tá tràng có Helicobacter pylori tại Khoa Nhi Tiêu Hóa Bệnh Viện Nhi Đồng 1 và Nhi Đồng 2. Y học Thành phố Hồ Chí Minh, 2008. 13, 148-152.
12. Nguyễn Thị Út, Đặc điểm dịch tễ, lâm sàng và kết quả của một số phác đồ điều trị viêm, loét dạ dày-tá tàng do Helicobacter Pylori kháng kháng sinh ở trẻ em tại bệnh viện Nhi trung ương. 2016, Luận án Tiến sĩ y học, trường Đại học Y Hà Nội.
13. Nguyễn Thị Thu Cúc, Nguyễn Trung Kiên, and T.Đ. Long, Tình hình nhiễm helicobacter pylori, đặc điểm lâm sàng và hình ảnh nội soi ở trẻ viêm, loét dạ dày-tá tràng từ 6-15 tuổi tại Bệnh viện
Nhi đồng Cần Thơ. 2019.
14. Tăng Lê Châu Ngọc, Đặc điểm đề kháng kháng sinh và đáp ứng điều trị trên trẻ viêm dạ dày do Helicobacter pylori tại Bệnh viện Nhi đồng 2. Hồ Chí Minh, 2018.
15. Phạm Võ Phương Thảo, Võ Thị Thu Hà, and Nguyễn Thị Cự, Nghiên cứu tình trạng thiếu máu thiếu sắt ở trẻ viêm loét dạ dày tá tràng điều trị tại Khoa Nhi bệnh viện Trung ương Huế. 2019.