NGHIÊN CỨU TÌNH HÌNH SỬ DỤNG KHÁNG SINH TRONG ĐIỀU TRỊ VIÊM PHỔI CỘNG ĐỒNG CHO TRẺ EM TỪ 2 THÁNG ĐẾN 5 TUỔI TẠI KHOA NHI, BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG QUẢNG NAM

Abstract

Background: Pneumonia is a common disease in children, the main cause of illness and death for children under 5 years old. Objectives: To evaluate the characteristics and the appropriateness of antibiotic use patterns in the treatment of community-acquired pneumonia (CAP) for children from 2 months to 5 years old at the Department of Pediatrics, Quang Nam Central General Hospital.

Materials and methods: Cross-sectional, non-interventional description based on retrospective medical records of children from 2 months to 5 years old with a diagnosis of pneumonia and excluding cases of hospital-acquired pneumonia. The criteria set for evaluating the use of antibiotics was developed mainly based on the treatment guidelines of the Ministry of Health. Results: 170 medical records were enrolled, of which, 87.6% had pneumonia. Most patients were prescribed monotherapy regimens, and the third generation cephalosporins (C3G) were the most common antibiotic group in both initial (62.4%) and alternative regimens (47.1%). Based on the criteria set of our study, the rate of appropriate initial antibiotic regimen was 20.6%, and in terms of dose and frequency of administration, was 49.8% and 97.7%, respectively. After 5 days of treatment, 90 patients met the criteria for conversion from IV to PO, but 10 cases were converted (11.1%), of which only 2 cases were rational. Conclusions:   Appropriateness of choosing initial antibiotic regimens was still low, IV to PO conversion was not concerned. This suggests the need for developing local antibiotic guidelines and widespread education on the proper use of antibiotics for clinicians.