ĐẶC ĐIỂM NHIỄM KHUẨN HUYẾT DO TRỰC KHUẨN GRAM ÂM Ở TRẺ EM TẠI KHOA HỒI SỨC TÍCH CỰC CHỐNG ĐỘC BỆNH VIỆN NHI ĐỒNG CẦN THƠ

Abstract

Background: Sepsis is the most common cause of death in children worldwide. Objective: To investigate some clinical, subclinical characteristics, result of treatment of negative gram of septic children at Can Tho Children's Hospital. Materials and methods: To describe the clinical characteristics and evaluate the treatment outcomes on 25 children diagnosed with gram- negative sepsis at of Intensive Care - Poison control Department of Can Tho Children's Hospital between 9/2022 to 2/2024. Results: All patients, there were 68% of males and 32% of females. Clinical features included: 52 % of sepsis, 48 % of sepsis shock. The clinical of sepsis were: hyperthermia 92%, tachycardia 76%, tachypnea 48%. The paraclinical characteristics of sepsis: leukocytosis 60%, increased procalcitonin 77.8%, increased CRP 64.2%, The rate of Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii was 16%. The frequencies of drug-resistant organisms vary depending on strains. Resistance of gram-negative bacteria cephalosporine was high. The mortality rate in gram-negative sepsis was 24%. Conclusions: The entrance routes of bacteria were mainly digestive and respiratory; CRP, procalcitonin, blood leukocytes increased; Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii were three pathogens with high rates.