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EVALUATION OF ANTIOXIDANT ACTIVITY OF SALAZINIC ACID FROM THE LICH EXTRACT Parmotrema tinctorum
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Abstract
Background: Salazinic acid is a depsidone containing a lactone ring, found in some lichen species and commonly in the genus Parmotrema. Salazinic acid possesses many attractive biological activities such as antibacterial, antifungal, anticancer and blood sugar control activities... Studies have evaluated the antioxidant activity of this acid is still very limited, especially in Vietnam. Objectives: To Evaluate of antioxidant activity of salazinic acid isolated from lichen growing in Vietnam. Materials and methods: Salazinic acid isolated from acetone extract of the lichen Parmotrema tinctorum. Antioxidant activity was evaluated by DPPH free radical scavenging method, ABTS●+ free radical scavenging method, reducing power method (RP), and total antioxidant capacity method (TAC). Results: Salazinic acid shows antioxidant ability when investigated by DPPH, ABTS, RP and TAC methods with IC50 or OD0.5 values respectively IC50 2381.53 ± 22.13 μg/mL, IC50 3154, 99 ± 87.47 μg/mL, OD0.5 1572.11 ± 17.17 μg/mL, OD0.5 1499.50 ± 35.76 μg/mL. Conclusion: Salazinic acid shows its antioxidant potential using many different evaluation methods, promising to be an effective source of antioxidants for further applied research.
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Keywords
Lichen, salazinic acid, antioxidant
References
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