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COMPARISON OF CLINICAL AND SUBCLINICAL OF OUTPATIENT MANAGEMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT THE RESPIRATORY CLINIC OF CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2 PHASES 7/2019-7/2020 AND 7/2020-7/2021
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Abstract
Background: In the complicated COVID-19 pandemic, COPD patients encountered many obstacles in getting regular check-ups and taking medicine during the lockdown, which led to the interruption of care for COPD and difficulties in COPD management. Objectives: To describe and evaluate the clinical and subclinical changes of COPD patients managed at Can Tho University of Medicine and Pharmacy Hospital in 2 periods: pre-COVID-19 pandemic (7/2019-7/2020) and during pandemic (7/2020-7/2021), assess the level of treatment adherence of patients during the COVID-19 pandemic. Materials and methods: All patients who came for COPD examination at the respiratory clinic of Can Tho University of Medicine and Pharmacy Hospital from 7/2019 to 7/2021. Results: There was no clinical difference in characteristics and symptoms, (p>0.05). mMRC3 during the pandemic increased more than before the pandemic. The average exacerbation of hospitalization decreased (before pandemic: 0.791.573 exacerbations/patient, during pandemic: 0.591.385 exacerbations/patient, p=0.041). In subclinical, increased Gaensler index (stage 1:55.8 15.0%, stage 2:61.9 ± 12.7%, p=0.039), indexes FEV1, FEV1%, FVC, FVC%. Ratio and number of eosinophils have no significant difference. The study also found that: the adherence rate of COPD patients is low (good: 38.8%, moderate: 48%, poor: 13.2%), and there are many factors affecting adherence. Conclusion: During the COVID-19 pandemic, there was a decrease in acute exacerbations requiring hospitalization of COPD patients and the level of adherence of COPD patients in this period was not high. There were many reasons leading to poor adherence to medication in COPD patients.
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Keywords
COPD, COPD during COVID-19 panndemic
References
2. Morisky DE, Ang A, Krousel-Wood M, Ward H. Predictive Validity of a Medication
Adherence Measure for Hypertension Control, Journal of Hypertension. 2008. 10(5), 348-354, doi: 10.1111/j.1751-7176.2008.07572. x.
3. Yvette Farrugia, Bernard Paul Spiteri Meilak. The Impact of COVID-19 on Hospitalized COPD Exacerbations in Malta, Hindawi Pulmonary Medicine, 2021:5533123, doi: 10.1155/2021/5533123.
4. González J, Moncusí-Moix A et al. Clinical Consequences of COVID-19 Lockdown in Patients With COPD: Results of a Pre-Post Study in Spain, Chest. 2021. 160(1), 135-138, doi: 10.1016/j.chest.2020.12.057.
5. Dương Thị Thanh Vân, Trương Thị Như Hảo và cộng sự. Bạch cầu ái toan- Dấu ấn sinh học tiên lượng đợt cấp bệnh phổi tắc nghẽn mạn tính, Tạp chí Y Dược Cần Thơ. 50/2022, 1-7.
6. Kolsum U, Southworth T, et al. Blood eosinophil counts in COPD patients compared to controls, Eur Respir J. 2019. 54: 1900633, doi: 10.1183/13993003.00633-2019.
7. Nguyễn Hoài Thu. Đánh giá tuân thủ điều trị và kỹ thuật sử dụng các thuốc dạng hít trên bệnh nhân bệnh phổi tắc nghẽn mãn tính tại bệnh viện Bạch Mai, Luận văn thạc sĩ Dược học, Trường Đại học Y Dược Hà Nội. 2016.
8. Tạ Hữu Ánh, Nguyễn Ngọc Tâm. Đánh giá thực trạng tuân thủ điều trị ở bệnh nhân bệnh phổi tắc nghẽn mạn tính điều trị ngoại trú, Tạp chí Y học Việt Nam. 2021. 508(2), 213-217.
9. Phạm Thành Soul, Đam Van Cuong et al. Medication Adherence of Vietnamese Outpatients with Chronic Diseases during the COVID-19 Pandemic, Trop.Med. Infect, 2022. 7(6), 101, doi: 10.3390/tropicalmed7060101.
10. Kvarnström K, Westerholm A, et al. Factors Contributing to Medication Adherence in Patients with a Chronic Condition: A Scoping Review of Qualitative Research, Pharmaceutics. 2021. 13(7):1100, doi: 10.3390/pharmaceutics13071100.
11. Kaye L, Theye B, et al. Changes in medication adherence among patients with asthma and COPD during the COVID-19 pandemic, J. Allergy Clin Immunol. Pract. 2020. 8(7), 2384– 2385, doi: 10.1016/j.jaip.2020.04.053.