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Date Published: 27/05/2024
Online Published: 27/05/2024
Abstract Views: 100
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DOI: https://doi.org/10.58490/ctump.2024i74.2382
Issue
No. 74 (2024)
Section
Article
How to Cite
Ong , Q. T., Huynh , T. L., Lam , D. T., Van , T. C., Quan , K. P., Nguyen, T. T., & Le , M. T. (2024). EVALUATION OF CERVICAL PESSARY AND PROGESTERONE IN PRETERM BIRTH PREVENTING AT 16-28 WEEKS GESTATION AT CAN THO GYNECOLOGY OBSTETRICS HOSPITAL IN 2022-2024. Cantho Journal of Medicine and Pharmacy, 74, 112-118. https://doi.org/10.58490/ctump.2024i74.2382

EVALUATION OF CERVICAL PESSARY AND PROGESTERONE IN PRETERM BIRTH PREVENTING AT 16-28 WEEKS GESTATION AT CAN THO GYNECOLOGY OBSTETRICS HOSPITAL IN 2022-2024

Quoc Thai Ong 1,, Huỳnh Thanh Liêm2, Lâm Đức Tâm1, Thuy Cam Van 2, Kim Phung Quan 1, Nguyễn Thanh Thủy2, Lê Minh Triết2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho Gynecology Obstetrics Hospital

Main Article Content

Abstract

Background: Preterm birth is the leading cause of death in newborns. Preterm birth also leads to many physical and mental problems and is an economic burden for families and society. Therefore, effective screening and prevention of preterm birth brings many benefits to the quality of the population and future life. Objectives: To evaluate the results of preterm birth prevention using a cervical pessary and progesterone between 16-28 weeks and different factors related to the effectiveness of prolonging gestation. Materials and method: A case series study was conducted on 60 cases pregnant women between 16-28 weeks with a short cervical length who were prevented from preterm birth with an Arabin pessary and progesterone at Can Tho Gynecology Obstetrics Hospital from September, 2022 to December 2023. Results: The birth rate at ≥34 weeks was 90%, and at ≥ 37 weeks was 55%. The average time from intervention to birth was 98.9 ± 36.6 days. The most common side effectisincreased vaginal discharge accounting for 30%. Cervical funneling increases the risk of preterm birth <34 weeks with statistical significance, with an odds ratio of 7.0 (p=0.038; CI 1.1-43.0). Conclusion: Using the Arabin pessary and progesterone for preventing preterm birth in pregnant women is an effective method, simple, method with a low side effect rate.

Article Details

Keywords

Arabin pessary, prevention of preterm birth, hospital

References

1. Chawanpaiboon S, Vogel JP, Moller AB, Lumbiganon P, Petzold M, et al. Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health. 2019. 7(1), e37-e46, DOI: 10.1016/S2214-109X(18)30451-0.
2. World Health Organization WHO. Preterm birth. World Health Organization. [Internet], 10 May 2023 [cited 16 February 2024]. Available from: https://www.who.int/news-room/fact-sheets/detail/preterm-birth.
3. Goya M, de la Calle M, Pratcorona L, Merced C, Rodó C, et al. Cervical pessary to prevent preterm birth in women with twin gestation and sonographic short cervix: a multicenter randomized controlled trial (PECEP-Twins). Am J Obstet Gynecol. 2016. 214(2), 145-152, DOI: 10.1016/j.ajog.2015.11.012.
4. Arabin B, Alfirevic Z, et al. Cervical pessaries for prevention of spontaneous preterm birth: past, present and future. Ultrasound Obstet Gynecol. 2013. 42(4), 390-309, DOI: 10.1002/uog.12540.
5. Vũ Nhật Khang. Tổng quan vòng nâng cổ tử cung Arabin trong dự phòng sinh non. Y học sinh sản. 2020. 52(11), 46-49.
6. Daskalakis G, Zacharakis D, Theodora M, Antsaklis P, Papantoniou N, Loutradis D, Antsaklis A. Safety and efficacy of the cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth. J Perinat Med. 2018. 46(5), 531-537, DOI: 10.1515/jpm-2017-0009. 7. Đỗ Thị Minh Nguyệt. Đánh giá bước đầu kết quả dự phòng sinh non bằng vòng Arabin tại Bệnh viện Phụ sản thành phố Cần Thơ. Đề tài nghiên cứu khoa học cấp cơ sở. Bệnh viện Phụ sản thành phố Cần Thơ. 2020.
8. Thi Hoang Trang Nguyen. Cervical pessary in preterm birth prvention among singleton pregnant women with a short cervix and obtuse uterocervical angle: A Quasi-Experimental Study. CC BY 4.0.1-12. 2023. DOI:10.20944/preprints202308.0661.v1.
9. Stricker N, Timmesfeld N, Kyvernitakis I, Goerges J, Arabin B. Vaginal progesterone combined with cervical pessary: A chance for pregnancies at risk for preterm birth?. Am J Obstet Gynecol. 2016. 214(6), 739.e1-739.e10, DOI: 10.1016/j.ajog.2015.12.007.
10. Fox NS, Gupta S, Lam-Rachlin J, Rebarber A, Klauser CK, Saltzman DH. Cervical Pessary and vaginal progesterone in Twin Pregnancies with a short Cervix. Obstet Gynecol. 2016. 127(4), 625-630, DOI: 10.1097/AOG.0000000000001300.
11. Melcer Y, Kovo M, Maymon R, Bar J, Wiener I, Neeman O, Pekar-Zlotin M, Zimerman A. Arabin cervical pessary with vaginal progesterone versus vaginal progesterone for preventing preterm delivery. J Matern Fetal Neonatal Med. 2020. 33(20), 3439-3444, DOI: 10.1080/14767058.2019.1573894.
12. Daskalakis G, Zacharakis D, Theodora M, Antsaklis P, Papantoniou N, Loutradis D, Antsaklis A. Safety and efficacy of the cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth. J Perinat Med. 2018. 46(5), 531-537, DOI: 10.1515/jpm-2017-0009.