ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ MỤN TRỨNG CÁ MỨC ĐỘ TRUNG BÌNH BẰNG MINOCYCLIN UỐNG TẠI BỆNH VIỆN DA LIỄU THÀNH PHỐ CẦN THƠ NĂM 2022

Abstract

Background: Acne is a chronic skin disease, very common and common in adolescents. The progression of the disease can be self-limiting, but if the disease is not treated or treated incorrectly, it can leave later sequelae. Minocycline has many advantages compared to other antibiotics in the same tetracycline group. However, in Vietnam, there are not many specific studies on treating moderate acne with minocycline. Objectives: To describe the clinical characteristics and evaluate the results of the treatment of moderate acne with oral minocycline. Materials and methods: A descriptive cross-sectional study was conducted on  90 moderate acne vulgaris patients treated with minocycline (oral route). Results: The main distribution of acne lesions accounts for 100%. Papules and whiteheads are the most common (100%). The average GAGs score of acne is 22.98  3.2. The number of inflammatory and non-inflammatory lesions at 8 weeks decreased by 71.6% and 60.7%, respectively, compared to the time of T0. The difference was statistically significant with p<0.001. GAGs scores decreased significantly after 8 weeks from baseline. The rate of good and excellent response to minocycline treatment after 8 weeks of treatment was 53.4%, and the average response was 46.6%. 8.9% of patients had headaches, 6.7% had cases of dizziness, and 17.8% had digestive disorders. Conclusion: Treatment of moderate acne with minocycline has significantly improved clinical efficacy, especially for inflammatory lesions.