VALUE OF LDH TEST ON COVID-19 PATIENTS AT CAN THO GENERAL HOSPITAL IN 2020-2021

Minh Hieu Pham1,, Minh Trang Nguyen2, Thai Thanh Tam Tran1
1 Can Tho University of Medicine and Pharmacy
2 Can Tho General Hospital

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Abstract

  Background: COVID-19 is a global problem. LDH testing is of interest in differentiating severe COVID-19 patients. Objectives: 1. To determine the average of LDH levels in some severe illness and death in COVID-19 patients; 2. To determine the sensitivity and specificity of the LDH test in predicting some severe illness and death in COVID-19 patients. Materials and method: A cross-sectional descriptive study performed on 120 COVID-19 patients from June 2020 to October 2021. Result: The mean LDH concentration in the group of patients with non-severe and severe COVID-19 was 266 ± 118.5U/L, 384 ± 147.4U/L (p<0.001), in the group of patients not admitted to the ICU. and had an ICU admission was 301 ± 125.6U/L and 415 ± 152.8U/L (p<0.001), in COVID-19 patients without ARDS and with an ARDS was 311 ± 131.9U/L and 432 ± 149.2U/L (p<0.001), in the group of non-fatal and fatal patients was 311 ± 135U/L and 421 ± 147.6U/L (p<0.001). LDH test has sensitivity and specificity was 78.7% and 61.3%, respectively; 69.1% and 67.7%; 73.8% and 67.9%; 71.7% and 64.9% in predicting severe COVID-19 patients, ICU admission, ARDS, and death. Conclusions: LDH concentration are increased in patients with severe, with ICU, with ARDS and die. LDH test has good value in predicting severe COVID-19 patients, ICU, ARDS and death.

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References

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