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STUDY ON DRUG RELATED PROBLEMS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS USED IN INPATIENT TREATMENT IN A DEPARTMENT AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2022 – 2023
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Abstract
Background: During treatment with drugs, Drug Related Problems - DRP may appear and be harmful to the patient's health, costly and cause treatment failure. Many studies indicate that non-steroidal anti-inflammatory drugs (NSAID) are among the most popular drugs causing DRP. Objective: Investigate the characteristics of using NSAID and determine the incidence of DRP of NSAID in a department at Can Tho University of Medicine and Pharmacy Hospital in 2022-2023. Materials and methods: A cross-sectional descriptive study on 254 medical records of inpatient treatment using NSAID in the Traumatology and Orthopaedics Department at Can Tho University of Medicine and Pharmacy Hospital during 09/2022 – 02/2023. Results: The proportion of men in the study was higher than that of women (57.5%). The majority of patients were in the age group of under 60 years old (69.7%). The average of length of hospital stay was 6 ± 3.3 days. Diclofenac had the highest use rate (86.5%) and the lowest was meloxicam (0.8%). The rate of using NSAID by injection was 44.4% and for oral route was 55.6%. The incidence DRP was 19.7%, with average 1.7 DRP/ medical record. DRP on drug interactions between NSAID and other drugs accounted for the highest rate (48.2%) and the lowest was treatment without adequate prevention (2.4%). Conclusion: Research shows that DRP of NSAID still occurs in a certain proportion, determination and classification of DRP can help implement measures to prevent DRP in the future.
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Keywords
Non-steroidal anti-inflammatory drugs, drug related problems, inpatient patient
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