NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT TRÊN BỆNH NHÂN UNG THƯ NỘI MẠC TỬ CUNG TẠI BỆNH VIỆN UNG BƯỚU THÀNH PHỐ CẦN THƠ NĂM 2021 – 2023

Abstract

Background: Endometrial cancer ranks second among gynaecological malignancies, after cervical cancer. Surgical treatment, including radical hysterectomy and pelvic lymphadenectomy, is the most important component and is often applied to the majority of patients. Objectives: To determine clinical, paraclinical characteristics and assessment of treatment results of radical hysterectomy and pelvic lymphadenectomy. Materials and method: A cross-sectional descriptive study was conducted on 38 patients with endometrial cancer. They underwent laparotomy hysterectomy and pelvic lymphadenectomy at Can Tho City Oncology Hospital from March 2021 to March 2023. Patients were recorded for clinical characteristics, paraclinical, stage according to FIGO, and intraoperative assessment of tumor size, complications and complications of surgery, histopathology, and lymph node status. All the data was analyzed by SPSS 20.0.  Results: Vaginal bleeding is the most common symptom of endometrial cancer, with 91.5% of cases. Palpable uterine can be found in 45.8%. There was no rectal invasion, bladder invasion, or ovarian invasion on the CT scan. The minimum number of dissected lymph nodes is 3 nodes, the maximum is 40 nodes. The rate of lymph node metastasis is 13.6%. Stage IA accounts for the highest proportion (50.8%). intraoperative complications rate was low. Surgical complications using Clavien– Dindo classification grade 0 was 74.6%, grade 1 was 8.5%, grade 2 was 13.5%, and grade 5 was 3.4%. Tumor type and histology grade are predictive factors for lymph node metastasis (P < 0.05). Conclusion: Radical hysterectomy with pelvic lymphadenectomy is a safe and effective surgery that improves survival in the treatment of endometrial cancer