ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ UNG THƯ ĐẠI TRÀNG TÁI PHÁT TẠI BỆNH VIỆN UNG BƯỚU CẦN THƠ VÀ BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2017-2019

Abstract

Background: Colon cancer is common and the third leading cause of gastrointestinal cancer. Recurrent colon cancer is 30-40% of all cases. The risk depends of recurrence on features of primary tumor. Nowadays, many researchers have found risk factors of this condition after colon cancer treatments. These finding is very meaningful in a prognosis and treatment. Objectives: 1. To determine some feature of recurrent colon cancer in patients treated in Can Tho Oncology Hospital and Can Tho University of Medicine and Pharmacy Hospital from 2017 to 2019. 2. To evaluate outcomes of treatment in patients have recurrent colon caner in Cantho Oncology Hospital and Can Tho University of Medicine and Pharmacy Hospital from 4/2017 to 4/2019. Materials and methods: This was a descriptive, prospective, longitudinal study. All patients who had diagnoses with recurrent colon cancer treated in Can Tho City Oncology Hospital and Can Tho University of Medicine and Pharmacy Hospital from 04/2017 to 04/2019 were included in this study. Results: Thirty patients with recurrent colon cancer in which the T in TNM staging system (p=0.018) and stages of cancer according WHO (p=0.007) were related to recurrence and disease-free survival time. Treatment response of recurrent colon cancer accounted for 55.6%. Factor related to the level of response was number of recurrent positions (p=0.044). Factors that prolonged progression-free survival time were late relapse (p=.,002), recurrence in one position (p=0.045), response to chemotherapy (p=0.046). Conclusion: Patients with T3, T4, III stages have ratio of recurrence higher and DFS shorter than patients with T1, T2, I, II ones. Number of recurrent positions affect to response to treatment. Factors that prolong progression-free survival time of recurrent colon cancer are late relapse, recurrence in one site and response to chemotherapy.