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Date Published: 12/06/2023
Online Published: 12/06/2023
Abstract Views: 364
Views PDF: 200
Issue
No. 29 (2020)
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Article
How to Cite
Nguyen , V., Le , T. T. N., Dang, C. N., Thach, T. M. U., & Duong, T. T. L. (2023). STUDY THE METHOD OF ISOLATION AND IDENTIFICATION OF SOME ORGANIC COMPOUNDS PRESENTING IN CENTELLA ASIATICA L. – APIACEAE COLLECTED IN CAN THO. Cantho Journal of Medicine and Pharmacy, 29, 184-189. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1605

STUDY THE METHOD OF ISOLATION AND IDENTIFICATION OF SOME ORGANIC COMPOUNDS PRESENTING IN CENTELLA ASIATICA L. – APIACEAE COLLECTED IN CAN THO

Vinh Nguyen 1,, Thi Thuy Ngoc Le 2, Cao Nguyen Dang1, Tran Minh Uyen Thach1, Thi Truc Ly Duong1
1 Can Tho University of Medicine and Pharmacy
2 Can Tho University of Medicine and Pharmacy v

Main Article Content

Abstract

 Background: Centella asiatica (L.) Urb, Apiaceae, also known as asiatic pennywort, is a common plant in Viet Nam. This paper studies the extraction, isolation, refinement, structural identification and determination of some compounds in terrestrial part of Centella asiatica collected in Can Tho. Objectives: The result shows that at least one chemical compound presenting in Centella asiatica was isolated and determined the structure. Materials and methods: The terrestrial part of Centella asiatica was collected in Can Tho. The terrestrial part of Centella asiatica with suitable size is extracted by immersion with 50% ethanol. The extract is purified by adsorption on activated carbon then desorption through methanol. The methanol solution is fractioned by vacuum column chromatography. These fractions are further recrystallized for pure compounds. Chemical structures of the compounds are elucidated by NMR (1H-NMR). Results: From Centella asiatica (L.) Urb, one pure compound was isolated: palmitic acid (CA1). Conclusion: The obtained results are consistent with the research objectives. This result may contribute to the determination of the active components in asiatic pennywort and support further research in order to increase commercial value of asiatic pennywort.

Article Details

Keywords

Centella asiatica (L.) Urb, Apiaceae, asiatic pennywort, isolation

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