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Date Published: 12/06/2023
Online Published: 12/06/2023
Abstract Views: 103
Views PDF: 329
Issue
No. 29 (2020)
Section
Article
How to Cite
Huynh, C. T., Le , V. L., Nguyen , P. T., Le , Q. V., & Nguyen , H. T. (2023). THE EFFECTIVENESS OF ONDANSETRON AND EXAMETHASONE COMBINATION IN PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENT UNDERGOING LAPAROSCOPIC CHOLESCYSTECTOMY AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL. Cantho Journal of Medicine and Pharmacy, 29, 14-20. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1577

THE EFFECTIVENESS OF ONDANSETRON AND EXAMETHASONE COMBINATION IN PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENT UNDERGOING LAPAROSCOPIC CHOLESCYSTECTOMY AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Chien Thang Huynh1,, Vu Linh Le 1, Phuong Thanh Nguyen 1, Quoc Vinh Le 1, Huu Thong Nguyen 1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Postoperative nausea and vomiting (PONV) are a most common and distressing symptoms within the first 24 hours post-operatively, especially on biliary surgery. Therefore, management of PONV for patients is essential to the best recovery outcome for patients. Objectives: To evaluate the efficacy of combination of dexamethasone and ondansetron for postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Materials and methods: A prospective, cross sectional study was conducted with 64 patients who undergoing laparoscopic cholescystectomy with general anesthesia and IV 4 mg dexamethasone after induction, IV 8 mg ondansetron at ending of surgery. The incidence, severity and complication of PONV were observed within 06 hours postoperatively. Results: The incidence of PONV within 0–06 hours postoperatively was 14.9%. Rescue antiemetics was required in 1 patient (1.5%). In our study, the most frequently reported adverse effects were 9.0% shivering, 16.4% dizziness, 1.5% headache and 1.5% transient dyspnea. Conclusion: The incidence of complete response within 06 hours postoperatively is 85.1%.

Article Details

Keywords

Postoperative nausea and vomiting, dexamethason, ondansetron

References

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