NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ VIÊM MÀNG NÃO TẠI KHOA SƠ SINH BỆNH VIỆN NHI ĐỒNG CẦN THƠ

Abstract

Background: Neonatal meningitis is one of the common infections causing morbidity and mortality in the world and in Vietnam. Symptoms of meningitis patients will vary depending on the causative agent, age, gender, and duration of the disease. The diagnosis of meningitis can be difficult, especially in the neonatal period, because the clinical presentation is nonspecific and lumbar puncture can be delayed due to clinical instability. Objectives: To study the clinical and paraclinical characteristics and evaluate the results of meningitis treatment in the neonatal department of Can Tho Children's Hospital. Materials and methods: A cross-sectional descriptive study was conducted on 55 pediatric patients diagnosed with meningitis at The Neonatology department of Can Tho Children's Hospital. Results: Male children accounted for 58.2%. Common clinical symptoms were fever (61,8%), feeding intolerance (50,9%), lethargy (58,1%), and jaundice (32,7%). Testing for CSF protein increased 60%, CSF glucose compared with capillary glucose decreased in 23 cases (41.8%) and increased cells accounted for 52.7%. Treatment success rate accounted for 92.7% and failure rate 1.8%. Conclusions: Meningitis was a common bacterial infection in neonates, with nonspecific symptoms that may be associated with other medical conditions. The disease tends to be more common in boys. Symptoms were not specific, in which the common clinical symptoms were fever, feeding intolerance, lethargy. Cerebrospinal fluid test protein and white blood cells are increased but positive culture results are low. The average duration of treatment was 3-4 weeks. 1.8% failure rate.