ĐẶC ĐIỂM LÂM SÀNG, ĐIỆN CƠ VÀ KẾT QUẢ ĐIỀU TRỊ GIẢM ĐAU BỆNH THẦN KINH NGOẠI BIÊN ĐÁI THÁO ĐƯỜNG TYP 2 BẰNG PREGABALIN TẠI BỆNH VIỆN TIM MẠCH THÀNH PHỐ CẦN THƠ

Abstract

Background: Neuropathic pain has always been a common complication of diabetic peripheral neuropathy in the type 2 diabetes. Objectives: to determine clinical, electromyography characteristics and treatment results of painful type 2 diabetic neuropathy. Material and methods: A cross-section study over 60 type 2 diabetes patients diagnosed with neuropathic pain at Can Tho Cardiovascular Hospital from February 2019 to March 2020. Diagnostic criteria for type 2 diabetes according to ADA 2016 (American Diabetes Association). Determination of peripheral neuropathy according to the American Neurological Association when the patient has clinical symptoms on the DNE scale and abnormal nerve conduction rate and electromyography. SPSS 20.0 software was used to analyze data. Results: Regarding subjective sensory disorders, the most common symptoms were numbness at 28.3%; needles account for 40% and stiffness 20%. Objective feelings, common symptoms are tactile disturbances, accounting for 93.3%; having a sense of shallow pain accounts for 66.7%. The sense of tendon and bone reflection accounts for 23.3%. According to DNE assessment, 80% of patients have numbness in the feet or lower legs, 40% have pain. Electromechanical abnormalities recorded on electromechanical abnormalities recorded 55% with increased needle puncture potential, muscle tremors 40%, 35% motor unit voltage, 28.3% positive spike waves and 10 % have decreased aggregation. Before treatment, 100% of patients had moderate pain (5-6 points), after 3 months of treatment 98.3% felt little pain and 1.7% had no pain. On average, the feeling of pain was statistically significant before and after treatment (p <0.001). Conclusion: In patients with diabetic peripheral neuropathy, pregabalon demonstrated early.