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THE RESULT OF PRE-ECLAMPSIA FIRST TRIMESTER SCREENING AT CAN THO OBSTETRICS AND GYNECOLOGY HOSPITAL
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Abstract
Background: Pre-eclampsia – eclampsia is a disease with many complications for mother and fetus with a prevalence of about 3-5%. Early detection, timely prevention, appropriate monitoring and delivery are current models to manage; Objectives: Evaluation of screening results for pre-eclampsia - eclampsia by the Fetal Medicine Foundation formula in first trimester at Can Tho Obstetrics and Gynecology Hospital. Materials and methods: A cross-sectional study of 603 first trimester pregnant women in Outpatient Department - Can Tho Obstetrics and Gynecology Hospital from 6/2021 to 11/2022, using history factors, blood pressure measurement, uterine artery Doppler, PAPP-A, PlGF to determine the risk of pre-eclampsia according to the Fetal Medicine Foundation formula, high-risk pregnant women receive aspirin prophylaxis and continue to be monitored for pre-eclampsia; Results: 10.0% of pregnant women had high-risk results for preeclampsia. In which, 21.7% of pregnant women had pre-eclampsia, with 23.1% severe. There were 23.1% detected at gestational age <34 weeks, 7.7% when 34 - <37 weeks and 69.2% from 37 weeks. Conclusions: Screening for pre-eclampsia in first trimester using Fetal Medicine Foundation formular should be performed for pregnant women in Can Tho in particular and Vietnam in general in order to provide effective prevent solutions. especially low-dose aspirin.
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Keywords
pre-eclampsia, eclampsia, first trimester
References
2. Huỳnh Nguyễn Khánh Trang. Ứng dụng của sFlt-1 và PlGF trong quản lý tiền sản giật. Hội nghị Sản phụ khoa Việt - Pháp - Châu Á Thái Bình Dương lần thứ 19, Thành phố Hồ Chí Minh. 2019.
3. O’Gorman, N., Wright, D., Syngelaki, A., Akolekar, R., Wright, A., et al. Competing risks model in screening for preeclampsia by maternal factors and biomarkers at 11-13 weeks gestation. American journal of obstetrics gynecology. 2016. 214(1), 103.e1-103.e12, https://doi.org/10.1016/ j.ajog.2015.08.034.
4. O'Gorman, N., Wright, D., Poon, L. C., Rolnik, D. L., Syngelaki, A., et al. Multicenter screening for pre‐eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations. Ultrasound in Obstetrics Gynecology. 2017.
49(6), 756-760. https://doi.org/10.1002/uog.17455.
5. Rolnik, D. L., Wright, D., Poon, L. C., O’Gorman, N., Syngelaki, A., et al. Aspirin versus placebo in pregnancies at high risk for preterm preeclampsia. New England Journal of Medicine. 2017. 377(7), 613-622, DOI: 10.1056/NEJMoa1704559.
6. Huỳnh Thị Tuyết Mai, Võ Minh Tuấn. Nghiên cứu sàng lọc nguy cơ cao tiền sản giật bằng mô hình FMF tại Bệnh viện Quốc tế Thái Hòa. Tạp chí Y học Việt Nam. 2021. 503(2), 152-156, https://doi.org/10.51298/vmj.v503i2.789.
7. Trần Mạnh Linh. Nghiên cứu kết quả sàng lọc bệnh lý Tiền sản giật - Sản giật bằng xét nghiệm PAPP-A, siêu âm Doppler động mạch tử cung và hiệu quả điều trị dự phòng. Luận án Tiến sĩ Y học, Trường Đại học Y Dược - Đại học Huế, Huế. 2020.
8. Rezende, K. B. D. C., Cunha, A. J. L. A., Amim Jr, J., Oliveira, W. D. M., Leão, M. E. B., et al. Performance of Fetal Medicine Foundation Software for Pre-Eclampsia Prediction Upon Marker Customization: Cross-Sectional Study. Journal of Medical Internet Research. 2019. 21(11), e14738, DOI: 10.2196/14738.
9. Poon, L. C., Kametas, N. A., Valencia, C., Chelemen, T.,nNicolaides, K. H. Hypertensive disorders in pregnancy: screening by systolic diastolic and mean arterial pressure at 11-13 weeks. Hypertension in Pregnancy. 2011. 30(1), 93-107, https://doi.org/10.3109/10641955.2010.484086.
10. Gallo, D., Poon, L. C., Fernandez, M., Wright, D., Nicolaides, K. H. Prediction of preeclampsia by mean arterial pressure at 11-13 and 20-24 weeks' gestation. Fetal diagnosis therapy. 2014. 36(1), 28-37, https://doi.org/10.1159/000360287.