KHẢO SÁT NỒNG ĐỘ, TỶ LỆ THIẾU VITAMIN D VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN NỮ MÃN KINH THOÁI HÓA KHỚP GỐI NGUYÊN PHÁT TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ NĂM 2022-2023

Abstract

Background: Osteoarthritis of the knee is the most common musculoskeletal disease worldwide and ranked 13th among 310 disabling diseases globally in 2015. Objectives: Determination of concentration, prevalence of vitamin D deficiency and some related factors in postmenopausal women with primary knee osteoarthritis at Can Tho General Hospital in 20222023. Material and methods: Cross-sectional descriptive study with analysis on 95 naturally menopausal female patients with primary knee osteoarthritis being treated at Can Tho General Hospital from July 2022 to April 2023. Serum vitamin D concentration testing was performed on Roche's CobasE411 immunoanalyzer, vitamin D deficiency is determined when serum 25 (OH) D concentration is <50 nmol/L, data analysis using SPSS 18.0 software. Results: The overall rate of patients with vitamin D deficiency is 52.6%, patients with severe vitamin D deficiency accounted for 22.1%, vitamin D deficiency was 30.5%. Patients with osteoarthritis for ≥10 years have a vitamin D deficiency rate of 65.0%, higher than patients with osteoarthritis <10 years, 43.6%; There was a relationship between age, duration of degenerative joint disease, stage of degenerative joint disease, osteoporosis, hypertension, diabetes and vitamin D deficiency of patients with p<0.05. Conclusion: The prevalence of vitamin D deficiency in patients with knee osteoarthritis was quite high. Early detection of knee osteoarthritis and associated diseases was necessary for timely treatment, contributing to reducing vitamin D deficiency in patients.