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Date Published: 24/10/2023
Online Published: 24/10/2023
Abstract Views: 422
Views PDF: 142
Issue
No. 43 (2021)
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Article
How to Cite
Ngo, T. A. L., Nguyen, T. L. T., Tran, H. L., & Vo, T. Y. N. (2023). CHARACTERISTICS OF BACTERIOLOGICAL CAUSES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT KIEN GIANG PROVINCE GENERAL HOSPITAL IN 2020. Cantho Journal of Medicine and Pharmacy, 43, 81-88. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1084

CHARACTERISTICS OF BACTERIOLOGICAL CAUSES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT KIEN GIANG PROVINCE GENERAL HOSPITAL IN 2020

Tran Ai Linh Ngo1,, Thi Linh Tuyen Nguyen2, Hoang Lam Tran3, Thi Yen Nhi Vo1
1 Kien Giang Medical College
2 Can Tho University of Medicine and Pharmacy
3 Kien Giang University

Main Article Content

Abstract

Background: Exacerbations of chronic obstructive pulmonary disease (COPD) lead to hospitalization and death in COPD patients, with infectious causes accounting for 70-80%. Therefore, microbiological assessment to help choose the right antibiotic in the treatment of this disease is very important and has clinical significance. Objectives: 1. Describe the characteristics of pathogenic bacteria causing acute exacerbations of COPD at Kien Giang province General Hospital in 2020. 2. Investigate some related factors to infection with some common bacterial strains causing exacerbations of chronic obstructive pulmonary disease. Materials and methods: A crosssectional descriptive study was conducted on 400 medical records of COPD exacerbations were admitted to hospital for treatment at the Department of Respiratory Internal Medicine at Kien Giang General Hospital in 2020. Data processing method is using SPSS software. Results: COPD exacerbations caused by Gram-negative bacteria account for the majority (79.71%). Some common strains are Klebsiella ssp. (27.54%), Pseudomonas ssp. (20.29%) and Acinetobacter baumannii (17.39%). Klebsiella ssp. are highly resistant to cephalosporin, Pseudomonas ssp. are highly resistant to gentamycin and carbapenems; Acinetobacter baumannii are resistant to ciprofloxacin and cephalosporins. Gram-positive bacteria account for 20.29%. The most common strain is Streptococcus pneumonia (11.59%).They are highly resistant to betalactam. Some factors related to the risk of infection is not smoking reduces the risk of infection with Klebsiella spp. (OR = 0.02, p = 0.016). The risk of infection with Pseudomonas spp. is reduced in the absence of hypertension (OR = 0.067, p = 0.040), type 2 diabetes (OR = 0.11, p = 0.011), old pulmonary tuberculosis (OR = 0.11, p = 0.003). Conclusion: The majority of pathogenic bacteria are gram-negative. Common strains are Klebsiella ssp., Pseudomonas ssp., Streptococcus ssp., Acinetobacter baumannii.  Some factors related to the risk of infection such as smoking, having old tuberculosis, having hypertension, having type 2 diabetes.

Article Details

Keywords

COPD exacerbation, chronic obstructive pulmonary disease, bacteria

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