EFFICACY OF INTRATHECAL MORPHINE AND BUPIVACAINE AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER AT CANTHO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
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Abstract
Background: There have been many studies in using intrathecal morphine in the clinical practice of abdominal surgery. Laparoscopic colorectal surgery also requires a variety of methods of pain relief, so using intrathecal morphine to reduce postoperative pain in this surgery is important in clinical practice. The results showed that the level of pain relief in the first 24 hours after surgery was good, with a few side effects. Objectives: To assess the effectiveness of analgesic and side effects of intrathecal morphine combined with bupivacaine after laparoscopic colorectal surgery. Materials and Methods: This was a descriptive, cross-sectional study from May to December 2020, including 63 patients undergoing laparoscopic colorectal cancer surgery with a mixture of intrathecal morphine-bupivacaine before general anesthesia. The degree of analgesia was assessed based on VAS. The postoperative side effects observed were nausea and vomiting, respiratory depression, and pruritus. Results: The analgesic effect at rest and slight movement was 95.2%, and 88.9% respectively with VAS ≤ 3. The side effects were nausea and vomiting 6.3%, and pruritus 1.6%; both side effects: 3.2%. Conclusions: Intrathecal morphine 300 µg showed a safe and positive analgesic effect for laparoscopic colorectal cancer surgery.
Keywords
intrathecal morphine, laparoscopic colorectal surgery, analgesia, pain relief, VAS
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