OVERVIEW OF THE TREATMENT OF BLEEDING PEPTIC ULCERS

Thi Lan Huong Nguyen1, , Hieu Tam Huynh1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Peptic ulcer bleeding is a prevalent emergency condition with a high mortality rate. This famous state especially requires prompt diagnosis and treatment, and it is extremely critical that treating physicians have access to those tools that can effectively evaluate the patients' risks, allowing quick and effective treatments to improve their prognosis ultimately. Annually, varieties gastrointestinal associations from many countries worldwide, such as the European Society of Gastrointestinal Endoscope, American college of gastroenterology, Japan Gastroenterological Endoscopy Society, World Gastroenterology Organisation, along with many unions provided new recommendations in clinical practice guidelines. These new directions help prepare for peptic ulcer bleeding, which includes pre-endoscopy, endoscopy, and post-endoscopy management, respectively. These up-to-date suggestions are intended to help the treating doctors make the most appropriate treatment decisions for the sick people's condition. With those profound findings, approaching the diagnosis and treatment in peptic ulcer bleeding with new therapies and treatments helps to decrease mortality and total hospital costs, which can support saving hundreds of lives fighting every day to survive with a lower barrier of budget. 

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References

1. Barkun AN (2019), Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the international consensus group, Ann Intern Med 2019, 171, pp. 805– 822.
2. Gralnek I.M (2015), Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline, Endoscopy, 47, pp. 1-46.
3. Gralnek I.M (2021), Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021, European Society of Gastrointestinal Endoscopy, pp. 300 - 332.
4. George S (2018), High-dose vs. low-dose proton pump inhibitors post endoscopic hemostasis in patients with bleeding peptic ulcer: a meta-analysis and meta-regression analysis, Turk J Gastroenterol, 2018(29), pp.22–31.
5. Kichii S (2016), Evidence-based clinical practice guidelines for peptic ulcer disease 2015, J Gastroenterol, 51, pp. 177–194.
6. Laine L (2012), Management of patients with ulcer bleeding, Am J Gastroenterol, 107, pp. 345–60.
7. Laine L (2021), ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding, Am J Gastroenterol, 116, pp. 899–917.
8. Peery A.F (2019), Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: Update 2018, Gastroenterology,156, pp. 254–272.
9. Peter K et al. (2021), Helicobacter pylori, World Gastroenterology Organisation Global Guidelines, pp. 8-11.
10. Rosenstock S.J (2013), Improving quality of care in peptic ulcer bleeding: Nationwide cohort study of 13,498 consecutive patients in the Danish clinical register of emergency surgery, Am J Gastroenterol, 108, pp. 1449–1457.
11. Sung JJ (2018), Asia-Pacific working group consensus on nonvariceal upper gastrointestinal bleeding: an update 2018, Gut, 67, pp. 1757–1768.
12. Sverdén E (2018), Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study, Gastrointest Endosc, 88, pp. 242–250.
13. Tomoari K (2021), Evidence-based clinical practice guidelines for peptic ulcer disease 2020, J Gastroenterol, 56, pp.303–322.