CHARACTERISTICS AND RESULTS OF TREATMENT OF ACUTE PANCREATITIS ACCORDING TO THE DEGREE OF HYPERTRIGLYCERIDEMIA AT CAN THO CENTRAL GENERAL HOSPITAL IN 2019 - 2020
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Abstract
Background: Hypertriglyceridemia is a fairly common cause of acute pancreatitis(AP) after alcohol and gallstones. Hypertriglyceridemia is triglyceridemia concentration >150mg/dl (1.7mmol/l). Severe hypertriglyceridemia ≥1000mg/dl (11.3 mmol/l) is considered the cause of AP. Objectives: To compare some clinical and subclinical features and results of treatment of AP with two levels of hypertriglyceridemia <11.3mmol/l and ≥11.3mmol/l at the GastroenterologyHematology department in Can Tho Central General Hospital. Materials and methods: This was a cross-sectional descriptive study of 103 patients who were admitted to the hospital with AP. Results: Clinical symptoms and some laboratory tests didn’t differ between the two groups. The differences between the two groups were the mean values of amylasemia, glycemia, natremia, AST and ALT. In AP with hypertriglyceridemia <11.3mmol/l and ≥11.3mmol/l, the rate of hyperlipasemia was 87.09% vs 100%, hyperamylasemia was 66.13% vs 21.9%, hyperglycemia 58.1% vs 82.9%, hyponatremia 35.5% vs 73.2%, respectively. Ultrasound helped diagnose acute pancreatitis with an accuracy of 88.9% for TG <11.3mmol/l group and 95.1% for TG ≥ 11.3mmol/l group. Mortality was 4.9% in TG≥11.3mmol/l group. Conclusions: Compared with two groups of AP with TG <11.3mmol/l and ≥11.3mmol/l, there wasn’t a difference in clinical symptoms. Mean values of amylasemia, glycemia, natremia, AST, ALT were different between the two groups of AP. The rate of hyperamylasemia and hyperlipasemia >3 times also differed between the two AP groups. Although there wasn’t a difference in mortality rate, two patients died in the TG ≥11.3mmol/l group, accounting for 4.9%.
Keywords
acute pancreatitis, hypertriglyceridemia
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