STUDY ON USING DRUGS IN DIALYSIS PATIENTS AT DONG THAP MILITARY PEOPLE HOSPITAL IN 2019 - 2021

Thanh Tam Nguyen1,, Xuan Chu Duong1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Drugs used in the treatment of hemodialysis patients may increase toxicity because of decreased elimination when renal function is reduced, significantly decrease the effectiveness because of hemodialysis, or cause adverse reactions because of drugs interactions, accumulation of metabolites. Objectives: To survey characteristics of patients undergoing hemodialysis at the hospital; To determine the rate of drugs used on hemodialysis patients at the hospital. Materials and methods: A cross-sectional descriptive study was conducted on 210 medical records of hemodialysis patients at Dong Thap Military People Hospital from June 2019 to June 2021. Results: The researched sample consisted of 210 patients. The proportion of hemodialysis men was 1.9 times higher than that of women; 97.62% of patients have anemia, 87,62% patients with hypertension, 74.81% of patients on hemodialysis 3 times/week or more. The rate of patients having to use more than 5 drugs was high (41.74%). 88.10% of patients had to use cardiovascular blood pressure drugs, 76.29% of patients had a combination of 2 to 4 blood pressure - cardiovascular drugs, but 109/210 cases still had blood pressure higher than 140/90 mmHg. Conclusions: The risk of drug interactions or drug side effects is very high because patients on hemodialysis have many comorbidities and use many drugs. Many patients cannot control their blood pressure with medication.

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References

1. Bộ Y tế (2015), Quyết định số 3931/QĐ-BYT ngày 21/9/2015, Hướng dẫn chẩn đoán và điều trị một số bệnh về thận – tiết niệu.
2. Nguyễn Thị Hoài (2017), Nghiên cứu xây dựng danh mục tương tác thuốc tại khoa thận – tiết niệu, bệnh viện E, Khoá luận tốt nghiệp đại học ngành dược học, Đại học Quốc gia Hà Nội.
3. Nguyễn Tấn Dũng, Nguyễn Ngọc Khôi (2019), Sử dụng thuốc trên đối tượng đặc biệt,
Dược lâm sàng đại cương, Trường Đại học Y Dược thành phố Hồ Chí Minh, Nhà xuất bản Y học, tr. 265-328.
4. American Kidney Fund (2021), Kidney disease statistics. www.kidneyfund.org.
5. Australian Institute of Health and Welfare (2021). Cardiovascular disease, diabetes and chronic kidney disease - Australian facts: Prevalence and incidence. www.aihw.gov.au.
6. James PA, Ortiz E, et al. (2014) evidence-based guideline for the management of high blood pressure in adults: (JNC8). JAMA. 2014 Feb 5;311(5):507, pp 20
7. Lionel U. Mailloux, MP, FACP, Vito M. Campese, Hypertension in Chronic Dialysis Patients. Handbooks of dialysis therapy, 4th edition, Saunders Elsevier, Philadelphia, pp 857 – 884.
8. Liyanage T, Ninomiya T, Jha V, et al. (2015) Worldwide access to treatment for endstage kidney disease: A systematic review. Lancet. 2015, pp 1975-1982.
9. United states renal data system (2021), USRDS annual data report: Incidence, prevalence, patient characteristics, & modality. www.usrds.org.