STUDY ON THE SITUATION AND SOME FACTORS RELATED TO BACTERIA PRODUCING EXTENDED SPECTRUM BETALACTAMASE IN PATIENTS WITH COMPLICATED URINARY TRACT INFECTIONS AT CAN THO CENTRAL GENERAL HOSPITAL IN 2021-2022
Main Article Content
Abstract
Background: Urinary tract infections are common with increasing rates the antibiotic resistance recently, especially complicated urinary tract infections. Objectives: We aim to investigate the rate of ESBL-producing bacteria in patients with complicated urinary tract infections and some related factors at Can Tho Central General Hospital in 2021-2022. Materials and
methods: a descriptive cross-sectional study was performed on a total of 71 participants with complicated urinary tract infections inpatient treatment at Can Tho Central General Hospital in 2021-2022. Data collection methods were clinical examination, bacteria identification, antibiogram and direct interviews. The Data were analyzed by SPSS 18.0. Results: the prevalence of ESBLproducing bacteria in patients with complicated urinary tract infections was 32.4%. There are three
main factors associated with the prevalence of ESBL-producing bacteria in patients with complicated urinary tract infections: recurrent urinary tract infection, previous antibiotic use and diabetes mellitus. It was found that rate of ESBL-producing bacteria was higher than the other group, with a statistical significance, p<0.05. Conclusion: The rate of ESBL-producing bacteria in patients is quite high, which the factors are related to recurrent urinary tract infection, previous antibiotic use, and diabetes mellitus.
Article Details
Keywords
Complicated urinary tract infections, ESBL, related factors
References
2. Hội Tiết niệu Thận học Việt Nam (2013), “Hướng dẫn điều trị nhiễm khuẩn đường tiết niệu ở Việt Nam”. VUNA.
3. Phan Thị Thu Hồng và Nguyễn Trần Mỹ Phương (2012), “Khảo sát vi khuẩn tiết men betalactamase phổ rộng tại bệnh viện Bình Dân”, Tạp chí Y học TP. H ồ Chí Minh, 16(1), tr.285-301.
4. Nguyễn Thế Hưng (2016), “Đánh giá chẩn đoán và điều trị nhiễm khuẩn đường tiết niệu phức tạp”, Luận án Chuyên khoa cấp II, Đại học Y Dược TP. Hồ Chí Minh.
5. Ngô Xuân Thái, Lê Việt Hùng, Trần Lê Duy Anh và cộng sự (2015), “Nhiễm khuẩn đường tiết niệu do vi khuẩn tiết ESBL tại khoa Tiết niệu Bệnh viện Nhân Dân Gia Định, kết quả chẩn đoán và điều trị”, Tạp chí Y học TP. Hồ Chí Minh, 19(4), tr.80-87.
6. Vũ Thị Thơm (2018), “Nghiên cứu tình hình, lâm sàng, cận lâm sàng và đánh giá kết quả điều trị ở bệnh nhân Nhiễm khuẩn đường Tiết niệu tại Bệnh viện Đa khoa Trung ương Cần Thơ năm 2017-2018”, Luận văn Thạc sĩ Y học, Đại học Y Dược Cần Thơ.
7. Arne S., Arnfinn S., Irene S., et al. (2013), “Risk Factors for Community-Acquired Urinary Tract Infections Caused by ESBL-Producing Enterobacteriaceae –A Case–Control Study in a Low Prevalence Country”, PLOS ONE, vol.84, pp.1-7.
8. Hiep T. N. (2013), Bacterial infections of the genitourinary tract, Smith’s general urology, pp. 197- 222.
9. Jumana H. A., Tariq A., Alaa D., et al. (2019), “Urinary tract infection caused by extendedspectrum β-lactamase-producing bacteria: Risk factors and antibiotic resistance”, Pediatrics International, vol.61, pp.1127-1132.
10. Mengistu A., Getnet T., Alemseged A., et al. (2018), “Isolation of Extended-Spectrum β-lactamase- (ESBL) Producing Escherichia coli and Klebsiella pneumoniae from Patients with Community-Onset Urinary Tract Infections in Jimma University Specialized Hospital, Southwest Ethiopia”, Canadian Journal of Infectious Diseases and Medical Microbiology, vol.18, pp.1-8.
11. Schaeffer A. J., Schaeffer E. M. (2012), Infection of the urinary tract, Campbell-Walsh Urology, Saunders Elsevier, US, 10th Ed, pp.257-325.