CLINICAL MANIFESTATIONS AND SOME RELATED FACTORS OF HERPES ZOSTER AT CAN THO VENERO-DERMATOLOGY HOSPITAL

Qui Ngoc Pham 1,
1 Public Health station of Phung Hiep District, Hau Giang Province

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Abstract

Background: Shingles with burning cutaneous lesions is caused by reactivation of the varicella-zoster virus being inactivated in the nerve nodes. Objectives: (1) To describe clinical manifestations of herpes zoster at Can Tho Venero-Dermatology Hospital; (2) To identify some factors related to shingles at Can Tho Venero-Dermatology Hospital. Materials and methods: A cross-sectional descriptive study was conducted on 51 shingles patients admitted to Can Tho Venero-Dermatology Hospital from 5/2020 to 4/2021. Results: Most shingles patients were female with the rate of 61.9%, and male accounted for 38.1%. The proportion of >60 year-old patients was 54.9%. The rate of patients admitted to hospital ≤5 days after symptom onset accounted for 72.6%. Most of the lesions were distributed in the head, face, neck and torso; accounting for 33.6% and 38.1% respectively. The average superficiality of lesion was 56±29cm2. The average length of hospital stay of the patient was 7±3 days. Pain and blisters were 2 symptoms, accounting for the highest percentage with 57.5% and 54% respectively. The rate of mild, medium and severe illness: 58.4%; 36.3% and 5.3%. Occurrence in October, November and December, >50cm2 lesion were factors that correlated with the severity of the disease. Conclusion: Shingles is a recurrent skin disease in the elderly with diverse clinical manifestations. In particular, the appearance of vesicles and blisters on the skin with sizeable area, in the months of 10,11,12 are warning signs used to avoid undesirable consequences.

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References

1. Huỳnh Văn Bá và cộng sự (2021), Nghiên cứu đặc điểm lâm sàng và kết quả phối hợp điều trị tại chỗ bệnh Zona bằng Medlo tại Phòng khám Chuyên khoa Da liễu FOB Cần Thơ năm 2020 - 2021, Đề tài nghiên cứu khoa học liên trung tâm, Cần Thơ.
2. Nguyễn Lan Anh, Đặng Văn Em (2016), Nghiên cứu một số đặc điểm dịch tễ và lâm sàng bệnh zona tại Bệnh viện TƯQĐ 108, Tạp chí Y dược lâm sàng 108, 11(9), tr.294-299.
3. Bệnh viện Da liễu Trung ương và trường Đại học Y Hà Nội (2019), Hình ảnh lâm sàng, chẩn đoán và điều trị trong chuyên ngành Da liễu, Nhà Xuất bản Y học, Hà Nội.
4. Vũ Ngọc Vương và cộng sự (2019), Hiệu quả lâm sàng của điện châm kết hợp acyclovir trong điều trị bệnh zona, Tạp chí y học Việt Nam, 2 (479), tr.30-33.
5. Boris Ehrenstein et al (2019), Diagnosis, treatment and prophylaxis of herpes zoster, Z Rheumatol, 79(10), pp. 1009-1017.
6. Désirée van Oorschot et al (2021), A systematic literature review of herpes zoster incidence worldwide, Human Vaccines & Immunotherapeutics, https://doi.org/10.1080/21645515.2020.1847582.
7. Farhang Babamahmoodi et al (2015), Clinical Manifestations of Herpes Zoster, Its Comorbidities, and Its Complications in North of Iran from 2007 to 2013, Neurol Res Int, 2015: 896098.
8. Fawziah Marra et al (2020), Risk Factors for Herpes Zoster Infection: A meta-Analysis, Open Forum Infect Dis, 7(1): ofaa005.
9. Ho Soon Jung et al (2015), Epidemiological Study on the Incidence of Herpes Zoster in Nearby Cheonan, Korean J Pain, 28(3), pp. 193–197.
10. Hung Fu Tseng et al (2020), The Epidemiology of Herpes Zoster in Immunocompetent, Unvaccinated Adults ≥50 Years Old: Incidence, Complications, Hospitalization, Mortality, and Recurrence, J Infect Dis, 222(5), pp. 798–806.
11. Jae-Ki Choi, Sun Hee, Sanghyun Par et al (2019), Trends in varicella and herpes zoster epidemiology before and after the implementation of universal one-dose varicella vaccination over one decade in South Korea, 2003–2015, Human Vaccines & Immunotherapeutics, 15 (11), pp.2554-2560.
12. Kosuke Kawai, Barbara P.Yawn (2017), Risk Factors for Herpes Zoster: A Systematic Review and Meta-analysis, Mayo Clinic Proceedings, 92 (12), pp.1806-1821.
13. Peter G. E. Kennedy et al (2018), Clinical Features of Varicella-Zoster Virus Infection, Viruses, 10(11): 609.
14. Pragya A. Nair et al (2020), Herpes Zoster, StatPearls.
15. Uwe Wollina (2017), Variations in herpes zoster manifestation, Indian J Med, 145(3), pp. 294–298.