OPTIMIZATION PREPARATION PROCESS OF LOTUS LEAF EXTRACT POWDER
Main Article Content
Abstract
Background: Along with the development of pharmaceutical industry in Vietnam, the preparation of intermediate product such as dry or powder extract from medicinal herbs serves the increasing demand for production. For this reason, optimization of preparation process from lotus leaf was necessary. Objectives: Investigating some conditions affecting the preparation process of lotus leaf powder by spray drying method with BCPharSoft OPT software. Materials and methods: medicinal plant of lotus leaves. 20 formulations according to D-optimal model were carried out to optimize the preparation process of lotus leaf powder. Four independent variables were selected for the survey, including medicinal herbs/solvent ratio (X1 includes 1:15; 1:16; 1:17), alcohol content (X2 includes 40%; 50%; 60%), inlet air temperature (X3 includes 170 oC; 175 oC) and flow rate (X4 includes 4 rpm/mint; 5 rpm/min). Two dependent variables include drying performance (Y1), moisture content (Y2). Select extraction conditions and spray-drying conditions so that lotus leaf powder has the highest drying performance and lowest moisture content. Results: Determined the optimal parameters of preparation process including the ratio of medicinal herbs/solvents of 1;15, alcohol content of 60%, inlet air temperature of 173oC, flow rate of 4 rpm/min. Conclusion: Prepared lotus leaf powder by spray-drying method with drying performance of 9.23% and moisture content of 5.68%.
Article Details
Keywords
Lotus leaf powder, spray-drying, optimization, BCPharSoft OPT software
References
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