ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ Ở TRẺ BỆNH KAWASAKI TẠI BỆNH VIỆN NHI ĐỒNG THÀNH PHỐ CẦN THƠ NĂM 2020-2021

Abstract

Background: Kawasaki is an acute self-limited febrile illness featured by systematic vasculitis and predominantly occurs in children. Objectives: To describe the clinical and paraclinical characteristics of Kawasaki disease in children, its complications on coronary artery abnormality, and treatment outcomes using IVIG. Materials and methods: A cross-sectional descriptive study was conducted on 51 children with Kawasaki disease diagnosed at Can Tho Children’s Hospital. Gathered information in a pre-structured questionnaire was from medical documents with physical examination and subclinical results. Results: 74.5% patients with typical Kawasaki disease, male was more likely than female (60.8% compared to 39.2%, respectively); the most common age group was 12 months – 5 years old (58.8%). Kawasaki disease is characterized by fever and bilateral non-exudative conjunctivitis (100%); erythema of the lips and oral mucosa (98%), cervical lymphadenopathy (51%) and changes in extremities, rashes (86.3%). Laboratory evidence of a systematic inflammatory responses was performed through 60.8% children having number of leucocyte ≥15.000/mm³; 92.2% subjects having CRP >30 mg/L and 90.2% subjects having erythrocyte sedimentation rate in the first hour ≥40 mm/hour; Coronary artery aneurysms developed in 31.4% children. The rate of cured outcome using immunoglobulin (IVIG) was 92.1%; 02 cases of anaphylaxis, 02 cases needed the second time of using IVIG. Conclusion: The typical Kawasaki disease in children was common form. Children was diagnosed and treated using IVIG to effectively prevent coronary complications that can be harmful to children’s health.