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Date Published: 09/06/2023
Online Published: 09/06/2023
Abstract Views: 47
Views PDF: 40
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No. 40 (2021)
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Article
How to Cite
Nguyen , T. D., Kha , H. N., & Bo, K. P. (2023). COMPARISON OF LYMPHOCYTE/MONOCYTE RATIO WITH CHILD-PUGH, MELD, MELDNA SCORE IN CIRRHOTIC PATIENTS AT CLINICAL HEMATOLOGY –GASTROENTEROLOGY DEPARTMENT AT CAN THO CENTRAL GENERAL HOSPITAL. Cantho Journal of Medicine and Pharmacy, 40, 8-14. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/789

COMPARISON OF LYMPHOCYTE/MONOCYTE RATIO WITH CHILD-PUGH, MELD, MELDNA SCORE IN CIRRHOTIC PATIENTS AT CLINICAL HEMATOLOGY –GASTROENTEROLOGY DEPARTMENT AT CAN THO CENTRAL GENERAL HOSPITAL

Thi Diem Nguyen 1, Huu Nhan Kha 1,, Kim Phuong Bo2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho Central General Hospital

Main Article Content

Abstract

 Background: There are many classification scores that classify severity of cirrhosis, ChildPugh score are widely used, followed by MELD (Model for End Stage Liver Disease) score. MELD score are used in predicting mortality in cirrhotic patients awaiting for liver transplantation. The MELDNa table was developed from the MELD score used for a group of cirrhotic patients with low blood sodium concentration. The lymphocyte/monocyte ratio has also recently been used due to the presence of inflammation. This ratio plays an important role in assessing the outcome of cirrhotic patients. Objectives: To determine the correlation between the lymphocyte/monocyte ratio and the Child-Pugh, MELD, MELDNa scores in cirrhotic patients at the Clinical Hematology and Gastroenterology Department of Can Tho Central General Hospital in 2019. Materials and methods: 153 patients were diagnosed with cirrhosis of the liver. Cross-sectional descriptive studies with analysis were performed. Results: With 66.7% male, the mean age was 59.08 ± 12.98. The average Child-Pugh score was 9.3 ± 2.13, Child A was 9.8%, Child B was 44.4%, Child C was 45.8%. The average MELD score was 16.915 ± 7.12755, the lowest score was 6, the highest score was 40. The mean MELDNa score was 19.4510 ± 8.10534, the lowest score was 6 and the highest was 40. The mean lymphocyte/monocyte ratio was 2.006 ± 2.2020, the median was 1.7615 with the lowest value being 0.085227 and the highest was 25.3437. The lymphocyte/monocyte ratio was negatively correlated with the Child, MELD and MELDNa scores r=0.238, r=0.211 and r=0.245, respectively. Conclusion: The lymphocyte/monocyte ratio is inversely correlated with Child-Pugh, MELD and MELDNa scores.

Article Details

Keywords

Cirrhosis, Child-Pugh score, MELD, MELDNa, Lymphocyte/monocyte ratio

References

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