CLINICAL CHARACTERISTICS, PARACLINICAL, AND TREATMENT RESULTS OF EOSINOPHILIC MENINGITIS IN CHILDREN: A CASE SERIES

Abstract

Background: Recognizing clinical and paraclinical reduce morbidity and mortality from this disease. Objective: To investigate the association of factors, clinical and paraclinical characteristics, and treatment outcomes of Eosinophilic meningitis. Materials and methods: Reports on a series of diseases detected with eosinophilic meningitis at the Department of Infectious Diseases at Can Tho Children's Hospital. Results: the cause of admission was usually intermittent headache, fever, and vomiting. Neurological symptoms include lethargy, and a stiff neck, no focal neurological damage was noted. White blood cells count in the peripheral blood slightly increased or normal; increased number of cerebrospinal fluid white blood cells; no larvae was found in the CSF; ELISA technique to find parasite antigens in blood detected all 3 cases positive for Toxocara spp. The drugs were treated include Ceftriaxone, Vancomycin, Imipenem, Albendazole, and Prednisolone. All cases got stable treatment results and hospital discharge after treatment Conclusion: Eosinophilic meningitis, although rare, can occur and it is easy to miss the diagnosis in the early stages. Treatment with anthelmintics and steroids can be effective.