Article Sidebar

PDF
Date Published: 15/09/2023
Online Published: 15/09/2023
Abstract Views: 533
Views PDF: 292
DOI: https://doi.org/10.58490/ctump.2023i63.612
Issue
No. 63 (2023)
Section
Article
How to Cite
Nguyen, V. N., Nguyen, P. B. Q., & Huynh, M. P. (2023). RESEARCH CHARACTERISTICS AND VALUE OF COMPUTER TOMOGRAPHY IMAGES IN DIAGNOSIS OF HEPATOCELLULAR CARCINOMA AT CAN THO ONCOLOGY HOSPITAL IN 2021-2023. Cantho Journal of Medicine and Pharmacy, 63, 1-8. https://doi.org/10.58490/ctump.2023i63.612

RESEARCH CHARACTERISTICS AND VALUE OF COMPUTER TOMOGRAPHY IMAGES IN DIAGNOSIS OF HEPATOCELLULAR CARCINOMA AT CAN THO ONCOLOGY HOSPITAL IN 2021-2023

Van Nam Nguyen1,, Phuoc Bao Quan Nguyen1, Minh Phu Huynh2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho General Hospital

Main Article Content

Abstract

Background: Liver cancer is a major health problem in Viet Nam with the majority of patients being diagnosed at a late stage, leading to poor treatment outcomes and high mortality. Objectives: To determine characteristics and value of computer tomography of hepatocellular carcinoma. Materials and methods: Descriptive cross-sectional study, all patients with hepatic tumors were examined and/or treated at Can Tho Oncology Hospital from May 2021 to September 2023. Results: Patients over 60 years old accounted for the majority (64.7%), ratio of males to females was 2.1:1, common tumor size was >5 cm (85.3%), tumors usually appeared in the right liver (52.9%) and solitary tumors accounted for the most (73.5%). There are many types of tumor enhancement across phases, however, washout enhancement accounts for the highest rate (76.5%) and has high specificity (80%). The image of the intratumoral aneurysm, tumor capsule and portal vein thrombosis has a high specificity of 100%, 93.3% and 93.3%, respectively. Conclusions: Computed tomography images of hepatocellular carcinoma are various and highly valuable in the diagnosis of hepatocellular carcinoma.

Article Details

Keywords

Hepatocellular carcinoma, HCC, portal vein thrombosis

References

1. Chidambaranathan-Reghupaty S., Fisher P. B., Sarkar D. Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification. Adv Cancer Res. 2021. 149, 1-61, https://doi.org/10.1016/bs.acr.2020.10.001.
2. Diego S., Lucia F., Pierluca P. Epidemiological Aspects of Hepatocellular Carcinoma. Springer International Publishing. Cham. 2023.
3. Samant H., Amiri H. S., Zibari G. B. Addressing the worldwide hepatocellular carcinoma: epidemiology, prevention and management. J Gastrointest Oncol. 2021. 12(Suppl 2), S361S373, doi: 10.21037/jgo.2020.02.08.
4. Nguyễn Chấn Hùng và cộng sự. Xây dựng chiến lược quốc gia vấn đề Ung thư. Bộ Y tế. Hà Nội. 1997. 1-10.
5. Semaan S., Lewis S., Chatterji M., Song C., Besa C., et al. Hepatocellular carcinoma detection in liver cirrhosis: diagnostic performance of contrast-enhanced CT vs MRI with extracellular contrast vs gadoxetic acid. Eur Radiol. 2020. 30(2), 1020-1030, doi: 10.1007/s00330-01906458-4.
6. Trần Quang Tú, Trần Chí Dương Long, Đỗ Thị Hồng Tươi. Đặc điểm bệnh nhân ung thư biểu mô tế bào gan tại đơn vị ung thư gan mật và ghép gan - Khoa Ngoại gan mật tụy Bệnh viện Đại học Y Dược TP. HCM. Tạp chí Y học Việt Nam. 2021. 504(2), 20-25, https://doi.org/10.51298/vmj.v504i2.895.
7. Phạm Văn Hùng, Đoàn Hữu Thiển. Đặc điểm ung thư biểu mô tế bào gan của bệnh nhân đến khám tại Bệnh viện Đại học Y Hà Nội. Tạp chí Y học Việt Nam. 2022. 514(2), 254-259, https://doi.org/10.51298/vmj.v514i2.2642.
8. Nguyễn Phước Bảo Quân. Nghiên cứu đặc điểm hình ảnh và giá trị của cắt lớp vi tính vòng xoắn 3 thì trong chẩn đoán một số ung thư gan thường gặp. Đại học Y Dược Hà Nội. 2010. 62-126.
9. Rich N. E., Yopp A. C., Singal A. G., Murphy C. C. Hepatocellular Carcinoma Incidence Is Decreasing Among Younger Adults in the United States. Clin Gastroenterol Hepatol. 2020. 18(1), 242-248 e5, https://doi.org/10.1016/j.cgh.2019.04.043.
10. McGlynn K. A., Petrick J. L., El-Serag H. B. Epidemiology of Hepatocellular Carcinoma. Hepatology. 2021. 73 Suppl 1, 4-13, https://doi.org/10.1002/hep.31288.
11. Ling Y. H., Chen J. W., Wen S. H., Huang C. Y., Li P., et al. Tumor necrosis as a poor prognostic predictor on postoperative survival of patients with solitary small hepatocellular carcinoma. BMC Cancer. 2020. 20(1), 607, https://doi.org/10.1186/s12885-020-07097-5.
12. Lee J. H., Lee J. M., Kim S. J., Baek J. H., Yun S. H., et al. Enhancement patterns of hepatocellular carcinomas on multiphasicmultidetector row CT: comparison with pathological differentiation. Br J Radiol. 2012. 85(1017), e573-83, https://doi.org/10.1259/bjr/86767895.
13. Shafqat M. N., Javed S., Chouhdary M. A., Shafqat G., et al. Frequency of Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma: Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma. Pakistan Journal of Health Sciences. 2022. 3(5), 115-119, https://doi.org/10.54393/pjhs.v3i05.219.
14. Chartampilas E., Rafailidis V., Georgopoulou V., Kalarakis G., Hatzidakis A., et al. Current Imaging Diagnosis of Hepatocellular Carcinoma. Cancers. 2022. 14, 3997,
10.1016/bs.acr.2020.10.001.
15. Liu Y. I., Shin L. K., Jeffrey R. B., Kamaya A. Quantitatively defining washout in hepatocellular carcinoma. AJR Am J Roentgenol. 2013. 200(1), 84-9, https://doi.org/10.2214/AJR.11.7171.