ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG VẢY NẾN MỦ TẠI BỆNH VIỆN DA LIỄU THÀNH PHỐ CẦN THƠ NĂM 2021

Abstract

Backgroud: Pustular psoriasis is a rare and potentially life-threatening variant of psoriasis. Pustular psoriasis can present as a localized disease or with generalized widespread skin lesionstypes. Due to the rarity of these conditions and the questionable link to the common, plaquetype psoriasis, numerous therapies have shown variable results and most entities remain difficult to treat. Objectives: To investigate clinical and laboratory characteristics of pustular psoriatic patients at Can Thơ Hospital of Dermato-Venerology. Materials and Methods: A descriptive crosssectional study on 31 patients diagnosed with pustular psoriasis at Can Thơ Hospital of DermatoVenerology. Results: A total of 31 patients were included in this study, 100% were generalized type (31 cases). The mean age of patients was 36.16 ± 18.11 years old and the female/male ratio was 2.44/1. The most common clinical symptoms were itching (100%), followed by chills (12.9%) and joint pain (6.45%). Common physical symptoms are skin pustules (100%), nail lesions (58.1%), fever (32.2%), geographic tongue (6.45%). The subclinical features in patients with pustular psoriasis are increased white blood cell count (80.65%), anemia (45.16%), increased erythrocyte sedimentation rate (100%), decreased serum albumin (35.48%), increased liver enzymes (32.23%), decreased blood calcium (61.29%), increased serum CRP (90.32%). Conclusions: Pustular psoriasis is a severe form of psoriasis. Patients often have symptoms such as: pustular lesions on the skin, fever, nail lesions. Clinical examination noted: leukocytosis, increased erythrocyte sedimentation rate, increased serum CRP, increased liver enzymes, decreased blood calcium and decreased blood albumin.