RELATIONSHIP BETWEEN MEDICATION ADHERENCE AND DEPRESSION AMONG ELDERLY PATIENTS WITH HYPERTENSION IN GERIATRICS DEPARTMENT AT CAN THO CENTRAL GENERAL HOSPITAL

Van Thong Nguyen 1,2, Son Tung Vu 3, Thien Thang Tran 2, Huu Nhan Đoan 2, Thai Thong Nguyen 2, Minh Hoang Le 2, Snowdon John 4, Van Tuan Nguyen 1,3,
1 Hanoi Medical University
2 Can Tho University of Medicine and Pharmacy
3 Bach Mai Hospital
4 The University of Sydney

Main Article Content

Abstract

Background: Adherence to antihypertensive treatment plays an essential role in blood pressure control, reducing the risk of cardiovascular events. Depression, on the other hand, is a common psychiatric problem that has a great impact on the patient's health and the ability to adhere to treatment. Objective: Determining the prevalence of depression, adherence to antihypertensive medication treatment and analyzing the relationship between adherence to antihypertensive drugs with depression and some other factors in elderly patients with hypertension. Materials and methods: A cross-section study conducted among 382 elderly inpatients with hypertension in the Department of Geriatrics at Can Tho Central General Hospital 2020-2022. Assessing medication adherence based on GMAS and depression was defined by using the ICD-10 criteria. Logistic regression was used to determine the relationships. Results: The prevalence of depression was 31.8% and antihypertensive adherence was 86.5%. Elderly patients without depression have a higher rate of good adherence than the depressive group (OR=3.17, 95%CI: 1.63-6.19), (p<0,05). Conclusions: Screening and treatment of depression in the elderly supports improving health and increasing treatment adherence in these subjects.

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References

1. Ademola A. D, Boima V, Odusola A. O, Agyekum F, Nwafor C.E, Salako B. L (2019), Prevalence and determinants of depression among patients with hypertension: A cross-sectional comparison study in Ghana and Nigeria, Niger J Clin Pract, 22 (4), pp. 558-565.
2. Aroner S. A, St-Jules D. E, Mukamal K. J, Katz R, Shlipak M. G, Criqui M. H, et al. (2016), Fetuin-A, glycemic status, and risk of cardiovascular disease: The Multi-Ethnic Study of Atherosclerosis, Atherosclerosis, 248, pp. 224-9.
3. Ashok V.G, Ghosh S.S (2019), Prevalence of Depression among Hypertensive Patients Attending a Rural Health Centre in Kanyakumari, National Journal of Community Medicine, 10(3):pp. 172-5
4. Demirtürk E, Hacıhasanoğlu Aşılar R(2018), The effect of depression on adherence to antihypertensive medications in elderly individuals with hypertension, J Vasc Nurs, 36 (3), pp. 129-139.
5. Kozela M, Bobak M, Besala A, Micek A, Kubinova R, Malyutina S, et al. (2016), The association of depressive symptoms with cardiovascular and all-cause mortality in Central and Eastern Europe: Prospective results of the HAPIEE study, Eur J Prev Cardiol, 23 (17), pp. 1839-1847.
6. Maguire L. K, Hughes C. M, McElnay J. C (2008), Exploring the impact of depressive symptoms and medication beliefs on medication adherence in hypertension--a primary care study, Patient Educ Couns, 73 (2), 371-6.
7. Naqvi A. A, Mahmoud M. A, AlShayban D. M, Alharbi F. A, Alolayan S. O, Althagfan S, et al. (2020), Translation and validation of the Arabic version of the General Medication Adherence Scale (GMAS) in Saudi patients with chronic illnesses, Saudi Pharm J, 28 (9), pp. 1055-1061.
8. Nguyen T. H, Truong H. V, M. T. Vi, K. Taxis, T. Nguyen, K. T. Nguyen (2021), Vietnamese Version of the General Medication Adherence Scale (GMAS): Translation, Adaptation, and Validation, Healthcare (Basel), pp. 9 (11)
9. Son Y. J, Won M. H (2017), Depression and medication adherence among older Korean patients with hypertension: Mediating role of self-efficacy, Int J Nurs Pract, pp. 23 (3)
10. Yang Q, Chang A, Ritchey M. D, Loustalot F (2017), Antihypertensive Medication Adherence and Risk of Cardiovascular Disease Among Older Adults: A Population-Based Cohort Study, J Am Heart Assoc, pp. 6 (6).