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Date Published: 05/10/2022
Online Published: 05/10/2022
Abstract Views: 161
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DOI: https://doi.org/10.58490/ctump.2022i4.470
Issue
No. 4 (2022): ENGLISH ISSUE
Section
Article
How to Cite
Nguyen, T. T. T., Tran, N. A. T., Nguyen, L. B., Lac, T. K. N., Pham, T. T., & Huynh, V. B. (2022). CLINICAL FEATURES, TOTAL AND SPECIFIC IgE SERUM CONCENTRATIONS OF PATIENTS WITH ATOPIC DERMATITIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY. Cantho Journal of Medicine and Pharmacy, 4, 54-60. https://doi.org/10.58490/ctump.2022i4.470

CLINICAL FEATURES, TOTAL AND SPECIFIC IgE SERUM CONCENTRATIONS OF PATIENTS WITH ATOPIC DERMATITIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY

Thi Thuy Trang Nguyen1,, Nguyen Anh Thu Tran1, Le Bang Nguyen1, Thi Kim Ngan Lac1, Thanh Thao Pham1, Van Ba Huynh1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Atopic dermatitis is a common skin disease in children as well as in adults, with the important feature of being recurrent. Immune disorders (the role of Specific IgE serum) have a relation to the severity of the disease and the risk of allergy in patients. Objectives: 1). To describe the clinical features of patients with atopic dermatitis at Can Tho Hospital of DermatoVenereology in 2021; 2). To determine the total and specific IgE serum concentration in patients with atopic dermatitis at Can Tho Hospital of Dermato-Venereology in 2021. Materials and methods: A cross-sectional descriptive study was carried out on 50 patients with atopic dermatitis hospitalized at Can Tho Hospital of Dermato-Venereology. Results: The rate of itching and types of eczematous lesions accounted for 100%, skin lesions with typical morphology and age-specific patterns were approximately 92%, chronic or relapsing history held 80%, xerosis rate was up to 82%, early age of onset made up 18%, the rate of increase in total and specific IgE serum level in patients with atopic dermatitis was 54% and 84%, respectively, the mean total IgE serum concentration was 210.01 ± 157.88 IU/mL, the lowest was 6.54 IU/mL and the highest was 741.23 IU/mL. D. pteronyssinus and D. farina accounted for the highest proportion of respiratory allergens (46%), cocoa beans accounted for the highest proportion of food allergens (28%). Conclusions: Atopic dermatitis in adult patients associated with pruritus, D. pteronyssinus and D. farina in respiratory allergens and cocoa beans in food allergens was the most common. Total and specific serum IgE concentrations are often elevated in patients with atopic dermatitis.

Article Details

Keywords

Atopic dermatitis, Total IgE serum concentration, Specific IgE serum concentration

References

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