NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ CÁC YẾU TỐ LIÊN QUAN ĐẾN TÁI SỐC, THỞ MÁY Ở TRẺ EM SỐT XUẤT HUYẾT DENGUE NẶNG TẠI BỆNH VIỆN NHI ĐỒNG CẦN THƠ GIAI ĐOẠN 2024 - 2025

Abstract

  Background: Dengue fever is an infectious disease that can rapidly progress to severe conditions in children, requiring early recognition and timely management. Objectives: To describe the clinical and laboratory characteristics and factors associated with recurrent shock and mechanical ventilation in children with severe dengue at Can Tho Children’s Hospital during 2024–2025. Materials and methods: A descriptive cross-sectional analytical study was conducted on 52 hospitalized children diagnosed with severe dengue at Can Tho Children’s Hospital from 2024 to 2025. Results: The age group >10 years accounted for the highest proportion (59.6%), with a similar distribution between males and females. Children living in rural areas represented 69.2%, and the prevalence of overweight and obesity was 28.8%. In the recurrent shock group, oliguria (26.3%; p=0.04) was significantly more frequent compared to the non-recurrent shock group, while pleural effusion (84.2%; p=0.729) and prolonged shock (80%) were more frequent but not statistically significant. Among patients requiring mechanical ventilation, pleural effusion (100%; p=1), recurrent shock (100%; p=0.044), and oliguria (33,3%; p=0.037) were markedly more common. Elevated hematocrit was significantly associated with mechanical ventilation (p=0.031), whereas platelet count (p=0.589) and white blood cell count (p=0.415) showed no significant differences. Conclusion: Key clinical and paraclinical features serve as indicators for potential recurrent shock and mechanical ventilation, aiding in the early stratification and treatment of pediatric patients with severe dengue.