Article Sidebar

PDF
Issue: No. 92 (2025)
Section: Article
DOI: 10.58490/ctjump.2025i92.4291
Date Published: 25/10/2025
Views 9
Downloads 12
How to Cite
Tran, T. H., Huynh, T. L., Ho, L. H., Vo, X. B., & Le, V. N. T. (2025). STUDY ON CHARACTERISTICS OF CLINICAL, PARACLINICAL AND ASSESSMENT EARLY TREATMENT RESULTS OF BREAST CONSERVING SURGERY IN CLINICAL STAGE I-II BREAST CARCINOMA AT CAN THO ONCOLOGY HOSPITAL. Cantho Journal of Medicine and Pharmacy, 92, 126-132. https://doi.org/10.58490/ctjump.2025i92.4291

STUDY ON CHARACTERISTICS OF CLINICAL, PARACLINICAL AND ASSESSMENT EARLY TREATMENT RESULTS OF BREAST CONSERVING SURGERY IN CLINICAL STAGE I-II BREAST CARCINOMA AT CAN THO ONCOLOGY HOSPITAL

Trong Huu Tran1, , Thao Luat Huynh1, Long Hien Ho1, Xuan Bao Vo1, Vo Nhat Thanh Le1
1 Can Tho Oncology Hospital

Main Article Content

Abstract

Background: Breast cancer is the most common malignancy in women. Breast-conserving surgery (BCS) has been increasingly applied in the management of early-stage breast cancer due to its oncologic outcomes comparable to total mastectomy, while improving cosmetic results and reducing complication rates. Objectives: To describe clinical and paraclinical characteristics and evaluate early results of breast-conserving surgery for stage I and II breast carcinoma at Can Tho City Oncology Hospital. Materials and methods: A prospective interventional clinical study was conducted on 46 patients with stage I–II breast carcinoma treated with BCS at Can Tho Oncology Hospital. Results: The mean patient age was 48.4 and the mean tumor size was 2.2 cm. Tumors were located in the left breast 54.3%, predominantly in the upper outer quadrant (69.6%), and all were unifocal. Postoperative histopathology revealed invasive carcinoma of no special type in 97.8%, with grade 2 in 95.7%, negative lymphovascular invasion (67.4%), and no axillary lymph node metastasis in 69.6%. Immunohistochemistry showed hormone receptor positivity in 54.3%, HER2 negativity in 82.6%, and Ki67 ≥ 20% in 54.3%. The mean operative time was 103 minutes. Surgical techniques included wide local excision with primary closure (13%), glandular tissue flap (56.5%), and pedicled skin flap (30.5%). Postoperative complications occurred in 15.1%, with hematoma (4.3%), partial flap necrosis (4.3%) and infection (6.5%). Good and excellent cosmetic outcomes were achieved in 93.5%, and 91.3% reported satisfaction with their treatment. Conclusion: Breast-conserving surgery for early-stage breast cancer ensures oncologic safety while providing optimal cosmetic outcomes and high patient satisfaction. 

Keywords

Breast-conserving surgery, early breast cancer, mammary myocutaneousglandular flap, pedicle flap

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

References

1. V. Suzanne Klimberg, Tibor Kovacs, Isabel T. Rubio, Oncoplastic Breast Surgery Techniques for the General Surgeon, Springer. 2020. doi: https://doi.org/10.1007/978-3-030-40196-2.
2. Nicola R., Giuseppe C., Michela C., Werner A., John B., et al. Should oncoplastic breast conserving surgery be used for the treatment of early stage breast cancer? Using the GRADE approach for development of clinical recommendations. Breast. 2021. 57, 25-35, doi: https://doi.org/10.1016/j.breast.2021.02.013.
3. Hoàng Anh Dũng, Lê Hồng Quang, Lê Văn Quảng. Đánh giá kết quả sớm phẫu thuật bảo tồn ung thư vú có sử dụng kỹ thuật tạo hình T ngược. Tạp chí Nghiên cứu Y học. 2020. 150(2), 154–165, doi: https://doi.org/10.52852/tcncyh.v150i2.706.
4. Lê Hồng Quang, Nguyễn Văn Đức. Kết quả phẫu thuật bảo tồn ung thư vú áp dụng các kỹ thuật tạo hình với khối u tại vị trí ít nhu mô tuyến vú. Tạp chí Y học Việt Nam. 2022. 511(2), 65-69, doi: https://doi.org/10.51298/vmj.v511i2.2114.
5. Lê Hồng Quang, Hoàng Anh Dũng. Kết quả phẫu thuật bảo tồn ung thư vú có sử dụng kỹ thuật tạo hình Round Block cho khối u nửa trên tuyến vú. Tạp chí Y học Việt Nam. 2022. 511(2), 225-229, https://doi.org/10.51298/vmj.v511i2.2162.
6. Lê Hồng Quang. Áp dụng kỹ thuật tạo hình kiểu chữ B cải tiến trong phẫu thuật bảo tồn ung thư vú tại Bệnh viện K. Tạp chí Y học Việt Nam. 2020. 489(1), 119-122, doi: https://tapchiyhocvietnam.vn/index.php/vmj/article/view/2837.
7. Nuh Zafer Cantürk, Turgay Şimşek, Sibel Özkan Gürdal, Oncoplastic Breast-Conserving Surgery According to Tumor Location, Eur J Breast Health. 2021. 17(3), 220-233, doi: 10.4274/ejbh.galenos.2021.2021-1-2.
8. Ismail J., John B., Hani S., Atlas of Breast Surgery. Springer. 2020. doi: https://doi.org/10.1007/978-3-030-45951-2.
9. Walter P Weber, Monica Morrow, Jana de Boniface, Andrea Pusic, Giacomo Montagna, et al, Knowledge gaps in oncoplastic breast surgery, Lancet Oncol. 2020. 21(8), e375-e385, doi: 10.1016/S1470-2045(20)30084-X.
10. Shu-Ling Z., Jun S., Yan-Ru W., Yi-Jia G., Jian-Zhu Z., et al. Short-term outcomes and safety of radiotherapy for immediate breast reconstruction with autologous flap transfer following breastconserving surgery. BMC Cancer. 2021. 21(1), 214, doi: https://doi.org/10.1186/s12885-021-07915-4.